CHEBI:31175 - adefovir pivoxil

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ChEBI Name adefovir pivoxil
ChEBI ID CHEBI:31175
Definition An organic phosphonate that is the dipivoxil ester of adefovir. A prodrug for adefovir, an HIV-1 reverse transcriptase inhibitor, adefovir pivoxil is used to treat chronic hepatitis B viral infection.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
nephrotoxic agent
A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys.
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Related Structures
adefovir pivoxil is a Structural Derivative of
adefovir
Mass : 273.186
Formula : C8H12N5O4P
2469
phosphonic acid
Mass : 81.99580
Formula : H3O3P H3O3P
44976
phosphorus oxoacid
Definition : A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.
oxoacid
Definition : A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
carbonic acid
Mass : 62.02478
Formula : CH2O3
28976
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Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
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