CHEBI:31445 - cyclic ADP-β-D-ribose

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ChEBI Name cyclic ADP-β-D-ribose
ChEBI ID CHEBI:31445
ChEBI ASCII Name cyclic ADP-beta-D-ribose
Definition A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): ryanodine receptor agonist
A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Related Structures
cyclic ADP-β-D-ribose is a Functional Parent of
2'-phospho-cyclic ADP-ribose
Mass : 622.28830
Formula : C15H23N5O16P3
76081
cyclic ADP-β-D-ribose is a Structural Derivative of
ADP-beta-D-ribose
Mass : 559.318
Formula : C15H23N5O14P2
191409
nucleoside
Mass : 116.115
Formula : C5H8O3R2
33838
nucleobase
Definition : That part of DNA or RNA that may be involved in pairing.
phosphoric acid
Mass : 97.99520
Formula : H3O4P
26078
phosphorus oxoacid
Definition : A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.
oxoacid
Definition : A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
monosaccharide
Definition : Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(2O)H or polyhydroxy ketones H1[CHOH]n1C(2O)[CHOH]m1H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.
carbohydrate
Definition : Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
nucleotide
Definition : A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid.
cyclic ADP-β-D-ribose is a Conjugate Acid of
cyclic ADP-beta-D-ribose(2-)
Mass : 539.28460
Formula : C15H19N5O13P2
73672
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