CHEBI:31638 - fulvestrant

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ChEBI Name fulvestrant
ChEBI ID CHEBI:31638
Definition A 3-hydroxy steroid that is 17β-estradiol in which the 7α hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Secondary ChEBI IDs CHEBI:87729
Supplier Information
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Roles Classification
Biological Role(s): estrogen receptor antagonist
An antagonist at the estrogen receptor.
estrogen antagonist
A compound which inhibits or antagonises the biosynthesis or actions of estrogens.
Application(s): estrogen receptor antagonist
An antagonist at the estrogen receptor.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
estrogen antagonist
A compound which inhibits or antagonises the biosynthesis or actions of estrogens.
Related Structures
fulvestrant is a Structural Derivative of
estrane
Mass : 246.43080
Formula : C18H30
23966
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