CHEBI:32246 - tolvaptan

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ChEBI Name tolvaptan
ChEBI ID CHEBI:32246
Definition A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
Application(s): aquaretic
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
Related Structures
tolvaptan is a Functional Parent of
DM-4107
Mass : 480.950
Formula : C26H25ClN2O5
183656 		DM-4103
Mass : 478.930
Formula : C26H23ClN2O5
183655
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