CHEBI:3353 - candoxatril

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ChEBI Name candoxatril
ChEBI ID CHEBI:3353
Definition The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart failure.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:152166
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 3.4.24.* (metalloendopeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
Related Structures
candoxatril is a Structural Derivative of
indan-5-ol
Mass : 134.17510
Formula : C9H10O
59311 		candoxatrilat
Mass : 399.47850
Formula : C20H33NO7
3354
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