CHEBI:3962 - curcumin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name curcumin
ChEBI ID CHEBI:3962
Definition A β-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ZINC000003831425
Download Molfile XML SDF
Roles Classification
Chemical Role(s): ligand
Any molecule or ion capable of binding to a central metal atom to form coordination complexes.
radical scavenger
A role played by a substance that can react readily with, and thereby eliminate, radicals.
iron chelator

Biological Role(s): EC 1.1.1.21 (aldehyde reductase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25).
EC 1.1.1.205 (IMP dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides.
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2.
EC 1.8.1.9 (thioredoxin reductase) inhibitor
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9).
flavouring agent
A food additive that is used to added improve the taste or odour of a food.
biological pigment
An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
lipoxygenase inhibitor
A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
EC 3.5.1.98 (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
food colouring
A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199).
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
(via diarylheptanoid )
Application(s): hepatoprotective agent
Any compound that is able to prevent damage to the liver.
flavouring agent
A food additive that is used to added improve the taste or odour of a food.
nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
dye

contraceptive drug
A chemical substance that prevents or reduces the probability of conception.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
food colouring
A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199).
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
Related Structures
curcumin is a Functional Parent of
tetrahydrocurcumin
Mass : 372.41170
Formula : C21H24O6
67263
hydrazinocurcumin
Mass : 364.39450
Formula : C21H20N2O4
84340
dihydrocurcumin
Mass : 370.39580
Formula : C21H22O6
67262
curcumin 4'-O-beta-D-gentiotetraside
Mass : 1016.949
Formula : C45H60O26
145773
curcumin 4'-O-beta-D-gentiotrioside
Mass : 854.808
Formula : C39H50O21
145772
5-(2,2-diferuloylethen-1-yl)thalidomide
Mass : 636.60420
Formula : C35H28N2O10
74775
curcumin is a Structural Derivative of
trans-ferulic acid
Mass : 194.18400
Formula : C10H10O4
17620
Graph View Tree View
panning
Move up
Move left
Move down
Move right
Graph compression

Simplified view Show me the possible minimal nodes in this graph
Full view Show me all the nodes in this graph
Personalised view Create your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity (e.g. molecular entity)
My hidden entities
Edit
curcumin
ketone
molecular entity
chemical entity
hydroxides
molecule
ether
oxygen molecular entity
polyphenol
heteroorganic entity
chalcogen molecular entity
main group molecular entity
carbon group molecular entity
cyclic compound
homocyclic compound
carbocyclic compound
hydrogen molecular entity
aromatic compound
organic aromatic compound
s-block molecular entity
p-block molecular entity
organic hydroxy compound
organic cyclic compound
benzenoid aromatic compound
phenols
aromatic ether
polyatomic entity
carbonyl compound
organic oxo compound
organochalcogen compound
organooxygen compound
heteroatomic molecular entity
diketone
organic molecular entity
enone
alpha,beta-unsaturated ketone
beta-diketone
organic molecule
diarylheptanoid
olefinic compound
+Zoom in
-Zoom out
Download
Enter fullscreen