CHEBI:421707 - abacavir

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ChEBI Name abacavir
ChEBI ID CHEBI:421707
Definition A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:441792, CHEBI:2360, CHEBI:193608, CHEBI:520984, CHEBI:525912
Supplier Information
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Roles Classification
Biological Role(s): drug allergen
Any drug which causes the onset of an allergic reaction.
HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): drug allergen
Any drug which causes the onset of an allergic reaction.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Related Structures
abacavir is a Functional Parent of
abacavir 5'-glucuronide
Mass : 462.45640
Formula : C20H26N6O7
64189
abacavir 5'-carboxylic acid
Mass : 300.31580
Formula : C14H16N6O2
64192
6-de(cyclopropylamino)-6-(2-methylazetidin-1-yl)abacavir
Mass : 300.366
Formula : C15H20N6O
149426
6-de(cyclopropylamino)-6-(2,2-dimethylazetidin-1-yl)abacavir
Mass : 314.393
Formula : C16H22N6O
149430
6-de(cyclopropylamino)-6-(azetidin-1-yl)abacavir
Mass : 286.339
Formula : C14H18N6O
149431
6-de(cyclopropylamino)-6-(3-isopropoxyazetidin-1-yl)abacavir
Mass : 344.419
Formula : C17H24N6O2
149432
abacavir monophosphate
Mass : 366.31220
Formula : C14H19N6O4P
64112
6-de(cyclopropylamino)-6-(3-fluoroazetidin-1-yl)abacavir
Mass : 304.329
Formula : C14H17FN6O
149434
6-de(cyclopropylamino)-6-(3-methoxyazetidin-1-yl)abacavir
Mass : 316.365
Formula : C15H20N6O2
149435
6-de(cyclopropylamino)-6-(isobutylamino)abacavir
Mass : 302.382
Formula : C15H22N6O
149437
6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir
Mass : 302.382
Formula : C15H22N6O
149438
6-de(cyclopropylamino)-6-(isopropylamino)abacavir
Mass : 288.355
Formula : C14H20N6O
149439
abacavir sulfate
Mass : 670.74460
Formula : 2C14H18N6O.H2O4S
2361
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