CHEBI:45716 - vorinostat

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name vorinostat
ChEBI ID CHEBI:45716
Definition A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Roles Classification
Biological Role(s): EC 3.5.1.98 (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
vorinostat is a Structural Derivative of
suberic acid
Mass : 174.19436
Formula : C8H14O4
9300 		hydroxylamine
Mass : 33.02996
Formula : H3NO
15429 		aniline
Mass : 93.12650
Formula : C6H7N
17296
Graph View Tree View
Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked