CHEBI:45980 - tacrine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name tacrine
ChEBI ID CHEBI:45980
Definition A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:45978, CHEBI:9389
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
Related Structures
tacrine is a Functional Parent of
bis(7)-tacrine
Mass : 492.699
Formula : C33H40N4
138435
tacrine is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
tacrine is a Conjugate Base of
tacrine(1+)
Mass : 199.276
187896
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