CHEBI:4781 - emetine

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ChEBI Name emetine
ChEBI ID CHEBI:4781
Definition A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
antiviral agent
A substance that destroys or inhibits replication of viruses.
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
autophagy inhibitor
Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
antiprotozoal drug
Any antimicrobial drug which is used to treat or prevent protozoal infections.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): emetic
Any agent that induces nausea and vomiting.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
expectorant
Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex.
antiamoebic agent
An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
antiprotozoal drug
Any antimicrobial drug which is used to treat or prevent protozoal infections.
Related Structures
emetine is a Functional Parent of
emetamine
Mass : 476.60722
Formula : C29H36N2O4
4780
emetine is a Structural Derivative of
cephaeline
Mass : 466.61240
Formula : C28H38N2O4
3533 		emetan
Mass : 360.53506
Formula : C25H32N2
36380
emetine is a Conjugate Base of
emetine(2+)
Mass : 482.664
Formula : C29H42N2O4
149548
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Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
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