CHEBI:5778 - hydrochlorothiazide

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name hydrochlorothiazide
ChEBI ID CHEBI:5778
Definition A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): diuretic
An agent that promotes the excretion of urine through its effects on kidney function.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
Related Structures
hydrochlorothiazide is a Structural Derivative of
sulfonic acid
Mass : 82.08008
Formula : H2O3S
29214 		oxoacid
Definition : A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
Graph View Tree View
panning
Move up
Move left
Move down
Move right
Graph compression

Simplified view Show me the possible minimal nodes in this graph
Full view Show me all the nodes in this graph
Personalised view Create your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity (e.g. molecular entity)
My hidden entities
Edit
+Zoom in
-Zoom out
Download
Enter fullscreen