microtubule-destabilising agent (CHEBI:61951)

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CHEBI:61951 - microtubule-destabilising agent

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ChEBI Name	microtubule-destabilising agent

ChEBI ID	CHEBI:61951

Definition	Any substance that interacts with tubulin to inhibit polymerisation of microtubules.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Midori Harris

Members of microtubule-destabilising agent Class

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G-1
Mass :412.283
Formula : C21H18BrNO3

nocodazole
Mass :301.32000
Formula : C14H11N3O3S

zoxamide

Definition : A racemate comprising equimolar amounts of (R)- and (S)-zoxamide. A fungicide used for the control of various fungal infections including blight in potatoes and tomatoes.

ethaboxam

Definition : A racemate comprising equimolar amounts of (R)- and (S)-ethaboxam. A fungicide used to control Oomycetes in vines and late potato blight. It is moderately toxic to birds, most aquatic species, honey bees and earthworms.

soblidotin
Mass :701.994
Formula : C39H67N5O6

vincaleukoblastine
Mass :810.97410
Formula : C46H58N4O9

(-)-demecolcine
Mass :371.42690
Formula : C21H25NO5

eribulin
Mass :729.89660
Formula : C40H59NO11

rigosertib sodium
Mass :473.470
Formula : C21H24NO8S.Na

rigosertib
Mass :451.490
Formula : C21H25NO8S

ustiloxin B
Mass :645.680
Formula : C26H39N5O12S

plinabulin
Mass :336.395
Formula : C19H20N4O2

carbendazim
Mass :191.18670
Formula : C9H9N3O2

eribulin mesylate
Mass :826.00200
Formula : C41H63NO14S

parbendazole
Mass :247.298
Formula : C13H17N3O2

dolastatin 10
Mass :785.100
Formula : C42H68N6O6S

podophyllotoxin
Mass :414.40530
Formula : C22H22O8

tubulozole

Definition : A racemate comprising equimolar amounts of (2R,4R)- and (2S,4S)-tubulozole. A synthetic anticancer drug that interferes with the structure and function of microtubules in both interphase and mitotic cells.

SB-743921
Mass :517.070
Formula : C31H33ClN2O3