CHEBI:65638 - CJ-01

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ChEBI Name CJ-01
ChEBI ID CHEBI:65638
Definition A sesquiterpenoid that is 4,4a,7,8,8a,9-hexahydronaphtho[2,3-b]furan substituted by methyl groups at positions 3, 5 and 8a and an oxo group at position 9 (the 4aS,8aS stereoisomer). It is isolated from the methanol extract of the whole plant of Chloranthus japonicus and acts as a chitin synthase inhibitor. CJ-01 also shows antifungal activity against various human and phytophathogenic fungi.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): EC 2.4.1.16 (chitin synthase) inhibitor
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Related Structures
CJ-01 is a Structural Derivative of
sesquiterpene
Definition : A C15 terpene.
terpene
Definition : A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH22C(CH3)CH2CH2].
alicyclic compound
Definition : An aliphatic compound having a carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system.
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