CHEBI:66248 - TMC-95D

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ChEBI Name TMC-95D
ChEBI ID CHEBI:66248
Definition A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. It includes a R-hydroxy group at position 11 and a (3-methyl-2-oxopentanoyl)amino group at position at position 18 with a S-methyl group. It acts as a proteasome inhibitor and is obtained from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
proteasome inhibitor
A drug that blocks the action of proteasomes, cellular complexes that break down proteins.
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is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
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