CHEBI:66669 - 8-hydroxymanzamine A

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ChEBI Name 8-hydroxymanzamine A
ChEBI ID CHEBI:66669
Definition An alkaloid that is manzamine A with a hydroxy substituent at position 8. Isolated from Pachypellina and Acanthostrongylophora, it exhibits inhibitory activity against Glycogen Synthase Kinase-3 (EC 2.7.11.26).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
anti-HSV-2 agent
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-2.
EC 2.7.11.26 (tau-protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
Related Structures
8-hydroxymanzamine A is a Structural Derivative of
manzamine A
Mass : 548.76080
Formula : C36H44N4O
66667
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