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ChEBI
> ChEBI Ontology
CHEBI:6838 - methotrimeprazine
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ChEBI Ontology
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ChEBI Name
methotrimeprazine
ChEBI ID
CHEBI:6838
Definition
A member of the class of phenothiazines that is 10
H
-phenothiazine substituted by a (2
R
)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively.
Stars
This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Biological Role
(s):
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
Application
(s):
phenothiazine antipsychotic drug
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Related Structures
methotrimeprazine is a
Structural Derivative
of
10H-phenothiazine
Mass : 199.27260
Formula : C12H9NS
ammonia
Mass : 17.03056
Formula : H3N
Graph View
Tree View
CHEBI:24431 chemical entity
CHEBI:23367 molecular entity
CHEBI:33579 main group molecular entity
CHEBI:33675 p-block molecular entity
CHEBI:33582 carbon group molecular entity
CHEBI:50860 organic molecular entity
CHEBI:72695 organic molecule
CHEBI:33832 organic cyclic compound
CHEBI:51958 organic polycyclic compound
CHEBI:51959 organic tricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:24532 organic heterocyclic compound
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:33285 heteroorganic entity
CHEBI:24532 organic heterocyclic compound
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:35352 organonitrogen compound
CHEBI:50047 organic amino compound
CHEBI:50996 tertiary amino compound
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:32952 amine
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:33245 organic fundamental parent
CHEBI:35573 organic mancude parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:35552 heterocyclic organic fundamental parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:50047 organic amino compound
CHEBI:50996 tertiary amino compound
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:32952 amine
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:33302 pnictogen molecular entity
CHEBI:51143 nitrogen molecular entity
CHEBI:35352 organonitrogen compound
CHEBI:50047 organic amino compound
CHEBI:50996 tertiary amino compound
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:32952 amine
CHEBI:32876 tertiary amine
CHEBI:6838 methotrimeprazine
CHEBI:33674 s-block molecular entity
CHEBI:33608 hydrogen molecular entity
CHEBI:33692 hydrides
CHEBI:37175 organic hydride
CHEBI:33245 organic fundamental parent
CHEBI:35573 organic mancude parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:35552 heterocyclic organic fundamental parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:36357 polyatomic entity
CHEBI:37577 heteroatomic molecular entity
CHEBI:33692 hydrides
CHEBI:37175 organic hydride
CHEBI:33245 organic fundamental parent
CHEBI:35573 organic mancude parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:35552 heterocyclic organic fundamental parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:25367 molecule
CHEBI:72695 organic molecule
CHEBI:33832 organic cyclic compound
CHEBI:51958 organic polycyclic compound
CHEBI:51959 organic tricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:24532 organic heterocyclic compound
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:33595 cyclic compound
CHEBI:33832 organic cyclic compound
CHEBI:51958 organic polycyclic compound
CHEBI:51959 organic tricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:24532 organic heterocyclic compound
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:33635 polycyclic compound
CHEBI:51958 organic polycyclic compound
CHEBI:51959 organic tricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:33671 heteropolycyclic compound
CHEBI:36688 heterotricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:5686 heterocyclic compound
CHEBI:33671 heteropolycyclic compound
CHEBI:36688 heterotricyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:24532 organic heterocyclic compound
CHEBI:38166 organic heteropolycyclic compound
CHEBI:26979 organic heterotricyclic compound
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:38093 phenothiazines
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:6838 methotrimeprazine
CHEBI:35568 mancude ring
CHEBI:35573 organic mancude parent
CHEBI:35571 mancude organic heterocyclic parent
CHEBI:36416 mancude organic heterotricyclic parent
CHEBI:37932 phenothiazine
CHEBI:37931 10
H
-phenothiazine
CHEBI:6838 methotrimeprazine
CHEBI:50906 role
CHEBI:33232 application
CHEBI:52217 pharmaceutical
CHEBI:23888 drug
CHEBI:35470 central nervous system drug
CHEBI:35471 psychotropic drug
CHEBI:35473 tranquilizing drug
CHEBI:35476 antipsychotic agent
CHEBI:65190 first generation antipsychotic
CHEBI:37930 phenothiazine antipsychotic drug
CHEBI:6838 methotrimeprazine
CHEBI:35488 central nervous system depressant
CHEBI:35473 tranquilizing drug
CHEBI:35476 antipsychotic agent
CHEBI:65190 first generation antipsychotic
CHEBI:37930 phenothiazine antipsychotic drug
CHEBI:6838 methotrimeprazine
CHEBI:35942 neurotransmitter agent
CHEBI:48560 dopaminergic agent
CHEBI:48561 dopaminergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:48278 serotonergic drug
CHEBI:48279 serotonergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:38323 cholinergic drug
CHEBI:48873 cholinergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:35480 analgesic
CHEBI:35481 non-narcotic analgesic
CHEBI:6838 methotrimeprazine
CHEBI:24432 biological role
CHEBI:35222 inhibitor
CHEBI:23924 enzyme inhibitor
CHEBI:76759 EC 3.* (hydrolase) inhibitor
CHEBI:60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor
CHEBI:5924 EC 3.4.21.* (serine endopeptidase) inhibitor
CHEBI:76779 EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
CHEBI:6838 methotrimeprazine
CHEBI:52206 biochemical role
CHEBI:23924 enzyme inhibitor
CHEBI:76759 EC 3.* (hydrolase) inhibitor
CHEBI:60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor
CHEBI:5924 EC 3.4.21.* (serine endopeptidase) inhibitor
CHEBI:76779 EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
CHEBI:6838 methotrimeprazine
CHEBI:52210 pharmacological role
CHEBI:35942 neurotransmitter agent
CHEBI:48560 dopaminergic agent
CHEBI:48561 dopaminergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:48278 serotonergic drug
CHEBI:48279 serotonergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:38323 cholinergic drug
CHEBI:48873 cholinergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:48706 antagonist
CHEBI:48561 dopaminergic antagonist
CHEBI:6838 methotrimeprazine
CHEBI:35480 analgesic
CHEBI:35481 non-narcotic analgesic
CHEBI:6838 methotrimeprazine
CHEBI:33281 antimicrobial agent
CHEBI:22587 antiviral agent
CHEBI:149553 anticoronaviral agent
CHEBI:6838 methotrimeprazine
Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked