CHEBI:70773 - capsazepine

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ChEBI Name capsazepine
ChEBI ID CHEBI:70773
Definition A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): capsaicin receptor antagonist
Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel.
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