CHEBI:75272 - splitomicin

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ChEBI Name splitomicin
ChEBI ID CHEBI:75272
Definition A benzochromenone that is 2,3-dihydro-1H-benzo[f]chromene substituted by an oxo group at position 3. It has been found to exhibit potential inhibitory activity against Sir2 proteins.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): Sir2 inhibitor
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2.
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
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