CHEBI:80131 - apelin-13

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ChEBI Name apelin-13
ChEBI ID CHEBI:80131
Definition A 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): autophagy inhibitor
Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
biomarker
A substance used as an indicator of a biological state.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
Related Structures
apelin-13 is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
apelin-13 is a Conjugate Base of
apelin-13(3+)
Mass : 1553.870
Formula : C69H114N23O16S
147395
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