Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> ChEBI Ontology
CHEBI:83275 - hypothemycin
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
hypothemycin
ChEBI ID
CHEBI:83275
Definition
A macrolide that is isolated from the cultured broth of
Hypomyces subiculosus
and shows antifungal activity and inhibits the growth of some human cancer cells.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
Roles Classification
Biological Role
(s):
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
hypothemycin is a
Structural Derivative
of
oxirane
Mass : 44.05256
Formula : C2H4O
Graph View
Tree View
CHEBI:24431 chemical entity
CHEBI:23367 molecular entity
CHEBI:33579 main group molecular entity
CHEBI:33675 p-block molecular entity
CHEBI:33582 carbon group molecular entity
CHEBI:50860 organic molecular entity
CHEBI:33285 heteroorganic entity
CHEBI:36962 organochalcogen compound
CHEBI:36963 organooxygen compound
CHEBI:36586 carbonyl compound
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:17087 ketone
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:51721 α,β-unsaturated ketone
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:35701 ester
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:25698 ether
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:26188 polyketide
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:83275 hypothemycin
CHEBI:24532 organic heterocyclic compound
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:72695 organic molecule
CHEBI:36587 organic oxo compound
CHEBI:36586 carbonyl compound
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:17087 ketone
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:51721 α,β-unsaturated ketone
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:33832 organic cyclic compound
CHEBI:24532 organic heterocyclic compound
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:33659 organic aromatic compound
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:33822 organic hydroxy compound
CHEBI:30879 alcohol
CHEBI:35681 secondary alcohol
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:26191 polyol
CHEBI:23824 diol
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:78840 olefinic compound
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:33304 chalcogen molecular entity
CHEBI:36962 organochalcogen compound
CHEBI:36963 organooxygen compound
CHEBI:36586 carbonyl compound
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:17087 ketone
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:51721 α,β-unsaturated ketone
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:35701 ester
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:25698 ether
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:26188 polyketide
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:83275 hypothemycin
CHEBI:25806 oxygen molecular entity
CHEBI:36963 organooxygen compound
CHEBI:36586 carbonyl compound
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:17087 ketone
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:51721 α,β-unsaturated ketone
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:35701 ester
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:25698 ether
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:26188 polyketide
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:83275 hypothemycin
CHEBI:24651 hydroxides
CHEBI:33822 organic hydroxy compound
CHEBI:30879 alcohol
CHEBI:35681 secondary alcohol
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:26191 polyol
CHEBI:23824 diol
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:33674 s-block molecular entity
CHEBI:33608 hydrogen molecular entity
CHEBI:24651 hydroxides
CHEBI:33822 organic hydroxy compound
CHEBI:30879 alcohol
CHEBI:35681 secondary alcohol
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:26191 polyol
CHEBI:23824 diol
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:36357 polyatomic entity
CHEBI:25367 molecule
CHEBI:72695 organic molecule
CHEBI:36587 organic oxo compound
CHEBI:36586 carbonyl compound
CHEBI:33308 carboxylic ester
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:17087 ketone
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:51721 α,β-unsaturated ketone
CHEBI:51689 enone
CHEBI:83275 hypothemycin
CHEBI:33832 organic cyclic compound
CHEBI:24532 organic heterocyclic compound
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:33659 organic aromatic compound
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:33595 cyclic compound
CHEBI:5686 heterocyclic compound
CHEBI:24532 organic heterocyclic compound
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:33832 organic cyclic compound
CHEBI:24532 organic heterocyclic compound
CHEBI:38104 oxacycle
CHEBI:25000 lactone
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:37407 cyclic ether
CHEBI:32955 epoxide
CHEBI:83275 hypothemycin
CHEBI:33659 organic aromatic compound
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:51026 macrocycle
CHEBI:63944 macrocyclic lactone
CHEBI:25106 macrolide
CHEBI:83275 hypothemycin
CHEBI:33655 aromatic compound
CHEBI:33659 organic aromatic compound
CHEBI:35618 aromatic ether
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:37577 heteroatomic molecular entity
CHEBI:24651 hydroxides
CHEBI:33822 organic hydroxy compound
CHEBI:30879 alcohol
CHEBI:35681 secondary alcohol
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:139588 α-hydroxy ketone
CHEBI:2468 secondary α-hydroxy ketone
CHEBI:83275 hypothemycin
CHEBI:26191 polyol
CHEBI:23824 diol
CHEBI:83275 hypothemycin
CHEBI:33853 phenols
CHEBI:83275 hypothemycin
CHEBI:50906 role
CHEBI:24432 biological role
CHEBI:35222 inhibitor
CHEBI:23924 enzyme inhibitor
CHEBI:71300 EC 2.* (transferase) inhibitor
CHEBI:76668 EC 2.7.* (
P
-containing group transferase) inhibitor
CHEBI:37699 protein kinase inhibitor
CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:52206 biochemical role
CHEBI:23924 enzyme inhibitor
CHEBI:71300 EC 2.* (transferase) inhibitor
CHEBI:76668 EC 2.7.* (
P
-containing group transferase) inhibitor
CHEBI:37699 protein kinase inhibitor
CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
CHEBI:83275 hypothemycin
CHEBI:25212 metabolite
CHEBI:75763 eukaryotic metabolite
CHEBI:76946 fungal metabolite
CHEBI:83275 hypothemycin
CHEBI:33281 antimicrobial agent
CHEBI:35718 antifungal agent
CHEBI:83275 hypothemycin
CHEBI:33232 application
CHEBI:52217 pharmaceutical
CHEBI:23888 drug
CHEBI:35610 antineoplastic agent
CHEBI:83275 hypothemycin
Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked