CHEBI:8459 - promazine

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ChEBI Name promazine
ChEBI ID CHEBI:8459
Definition A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB21431874, eMolecules:10556188, ZINC000038143761
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
Application(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
phenothiazine antipsychotic drug

antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
Related Structures
promazine is a Functional Parent of
promazine sulfoxide
Mass : 300.420
Formula : C17H20N2OS
145225
promazine is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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heterocyclic compound
promazine
promazine hydrochloride
molecular entity
chemical entity
organic heterocyclic compound
molecule
organic heterotricyclic compound
tertiary amine
amine
heteroorganic entity
pnictogen molecular entity
main group molecular entity
carbon group molecular entity
cyclic compound
polycyclic compound
heteropolycyclic compound
p-block molecular entity
organic cyclic compound
organonitrogen compound
polyatomic entity
heterotricyclic compound
phenothiazines
organic heteropolycyclic compound
organic amino compound
organic molecular entity
tertiary amino compound
nitrogen molecular entity
organic polycyclic compound
organic tricyclic compound
organic molecule
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