CHEBI:92053 - 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

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ChEBI Name 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione
ChEBI ID CHEBI:92053
Definition A quinolone that is quinoline-5,8-dione substituted by chloro and [2-(morpholin-4-yl)ethyl]amino groups at positions 6 and 7, respectively. It is a potent and irreversible inhibitor of Cdc25 isoforms.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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