CHEBI:9364 - suramin sodium

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ChEBI Name suramin sodium
ChEBI ID CHEBI:9364
Definition An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 2.7.11.13 (protein kinase C) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
GABA antagonist
A compound that inhibits the action of gamma-aminobutyric acid.
GABA-gated chloride channel antagonist

purinergic receptor P2 antagonist
An antagonist at purinergic P2 receptors
ryanodine receptor agonist
A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
Application(s): antinematodal drug
A substance used in the treatment or control of nematode infestations.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
angiogenesis inhibitor
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
GABA antagonist
A compound that inhibits the action of gamma-aminobutyric acid.
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