CHEBI:9448 - terbinafine

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ChEBI Name terbinafine
ChEBI ID CHEBI:9448
Definition A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 1.14.13.132 (squalene monooxygenase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132).
P450 inhibitor
An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
sterol biosynthesis inhibitor
Any compound that inhibits the biosynthesis of any sterol.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via allylamine antifungal drug )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via allylamine antifungal drug )
Related Structures
terbinafine is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
terbinafine is a Conjugate Base of
terbinafine(1+)
Mass : 292.43730
Formula : C21H26N
77615
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Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
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