CHEBI:9599 - (S)-timolol (anhydrous)

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ChEBI Name (S)-timolol (anhydrous)
ChEBI ID CHEBI:9599
ChEBI ASCII Name (S)-timolol (anhydrous)
Definition The (S)-(−) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:108531, CHEBI:108311
Supplier Information
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Roles Classification
Biological Role(s): beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
Related Structures
(S)-timolol (anhydrous) is a Structural Derivative of
1,2,5-thiadiazole
Mass : 86.11676
Formula : C2H2N2S
39469
(S)-timolol (anhydrous) is a Conjugate Base of
(S)-timolol(1+)
Mass : 317.430
188157
(S)-timolol (anhydrous) is a Enantiomer of
(R)-timolol
Mass : 316.42000
Formula : C13H24N4O3S
39466
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