Ketcher 03121911122D 1   1.00000     0.00000     0

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M  END
> <ID>
CHEBI:143120

> <NAME>
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine

> <DEFINITION>
A member of the class of quinazolines that is quinazoline which is substituted at positions 2 and 4 by 6-methylpyridin-2-yl and pyridin-4-ylnitrilo groups, respectively. It is an ALK5 and PKN3 kinase inhibitor.

> <STAR>
3

> <SYNONYM>
GW855857

> <IUPAC_NAME>
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine

> <FORMULA>
C19H15N5

> <MASS>
313.364

> <MONOISOTOPIC_MASS>
313.13275

> <CHARGE>
0

> <SMILES>
CC1=CC=CC(C2=NC3=CC=CC=C3C(NC4=CC=NC=C4)=N2)=N1

> <INCHI>
InChI=1S/C19H15N5/c1-13-5-4-8-17(21-13)19-23-16-7-3-2-6-15(16)18(24-19)22-14-9-11-20-12-10-14/h2-12H,1H3,(H,20,22,23,24)

> <INCHIKEY>
JONFDFIXMPXTRH-UHFFFAOYSA-N

> <DRUGBANK_ACCESSION>
DB07267

> <PDBECHEM_ACCESSION>
855

> <PUBMED_CITATION>
19285388

$$$$