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M  END
> <ID>
CHEBI:145431

> <NAME>
indisulam

> <DEFINITION>
A chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development.

> <STAR>
3

> <SYNONYM>
N(1)-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide; N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzenesulfonamide; E7070; E-7070

> <IUPAC_NAME>
N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide

> <INN>
indisulamum; indisulam; indisulam; indisulam

> <FORMULA>
C14H12ClN3O4S2

> <MASS>
385.840

> <MONOISOTOPIC_MASS>
384.99578

> <CHARGE>
0

> <SMILES>
C=1C=CC(=C2NC=C(C12)Cl)NS(C3=CC=C(C=C3)S(N)(=O)=O)(=O)=O

> <INCHI>
InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)

> <INCHIKEY>
SETFNECMODOHTO-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
165668-41-7

> <CHEMIDPLUS>
165668-41-7

> <DRUGBANK_ACCESSION>
DB06370

> <KEGG_DRUG_ACCESSION>
D04522

> <PDBECHEM_ACCESSION>
EF6

> <PUBMED_CITATION>
11677118; 12351604; 12439332; 12445024; 12556221; 14684331; 17285128; 18637887; 22349812; 28302793; 29660836

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