08180812472D 1 1.00000 0.00000 0 57 62 0 1 0 999 V2000 10.6707 -6.5843 0.0000 C 0 0 1 0 0 0 0 0 0 11.4666 -6.7998 0.0000 C 0 0 1 0 0 0 0 0 0 11.9124 -6.1080 0.0000 C 0 0 0 0 0 0 0 0 0 11.3961 -5.4673 0.0000 C 0 0 1 0 0 0 0 0 0 10.6272 -5.7618 0.0000 O 0 0 0 0 0 0 0 0 0 6.3923 -6.5747 0.0000 C 0 0 1 0 0 0 0 0 0 6.3923 -7.3997 0.0000 C 0 0 2 0 0 0 0 0 0 7.1007 -7.8101 0.0000 C 0 0 0 0 0 0 0 0 0 7.8133 -7.3997 0.0000 C 0 0 0 0 0 0 0 0 0 7.8133 -6.5747 0.0000 C 0 0 1 0 0 0 0 0 0 7.1007 -6.1602 0.0000 O 0 0 0 0 0 0 0 0 0 5.6780 -7.8153 0.0000 C 0 0 0 0 0 0 0 0 0 8.5294 -6.1664 0.0000 C 0 0 0 0 0 0 0 0 0 9.2433 -6.5789 0.0000 C 0 0 2 0 0 0 0 0 0 5.6762 -6.1664 0.0000 C 0 0 2 0 0 0 0 0 0 5.6737 -5.3415 0.0000 C 0 0 0 0 0 0 0 0 0 4.9624 -6.5789 0.0000 C 0 0 0 0 0 0 0 0 0 6.3876 -4.9248 0.0000 O 0 0 0 0 0 0 0 0 0 4.9576 -4.9290 0.0000 O 0 0 0 0 0 0 0 0 0 9.2356 -7.4048 0.0000 C 0 0 0 0 0 0 0 0 0 9.9453 -7.8212 0.0000 C 0 0 2 0 0 0 0 0 0 10.6639 -7.4123 0.0000 C 0 0 1 0 0 0 0 0 0 9.9541 -6.1695 0.0000 O 0 0 0 0 0 0 0 0 0 9.9398 -8.6462 0.0000 O 0 0 0 0 0 0 0 0 0 9.2221 -9.0519 0.0000 C 0 0 0 0 0 0 0 0 0 11.3761 -7.8317 0.0000 C 0 0 0 0 0 0 0 0 0 11.3918 -4.6388 0.0000 C 0 0 0 0 0 0 0 0 0 12.1919 -5.2482 0.0000 C 0 0 2 0 0 0 0 0 0 12.8344 -5.7598 0.0000 O 0 0 0 0 0 0 0 0 0 13.5237 -5.3068 0.0000 C 0 0 2 0 0 0 0 0 0 13.3046 -4.5110 0.0000 C 0 0 0 0 0 0 0 0 0 12.4799 -4.4748 0.0000 C 0 0 0 0 0 0 0 0 0 13.9330 -6.0193 0.0000 C 0 0 0 0 0 0 0 0 0 14.2356 -4.8875 0.0000 C 0 0 1 0 0 0 0 0 0 14.9915 -5.2202 0.0000 C 0 0 2 0 0 0 0 0 0 15.5405 -4.6025 0.0000 C 0 0 0 0 0 0 0 0 0 15.1212 -3.8906 0.0000 C 0 0 1 0 0 0 0 0 0 14.3158 -4.0669 0.0000 O 0 0 0 0 0 0 0 0 0 15.1677 -6.0260 0.0000 C 0 0 0 0 0 0 0 0 0 15.4540 -3.1343 0.0000 C 0 0 2 0 0 0 0 0 0 16.2795 -3.0482 0.0000 C 0 0 2 0 0 0 0 0 0 16.6085 -2.2960 0.0000 C 0 0 0 0 0 0 0 0 0 16.1205 -1.6284 0.0000 C 0 0 2 0 0 0 0 0 0 15.2994 -1.7180 0.0000 C 0 0 2 0 0 0 0 0 0 14.9664 -2.4753 0.0000 O 0 0 0 0 0 0 0 0 0 14.4719 -1.7121 0.0000 O 0 0 0 0 0 0 0 0 0 15.5125 -0.9161 0.0000 C 0 0 0 0 0 0 0 0 0 14.9246 -0.3391 0.0000 O 0 0 0 0 0 0 0 0 0 16.4560 -0.8733 0.0000 C 0 0 0 0 0 0 0 0 0 16.7634 -3.7154 0.0000 C 0 0 0 0 0 0 0 0 0 12.1877 -6.0732 0.0000 H 0 0 0 0 0 0 0 0 0 13.6470 -4.3030 0.0000 H 0 0 0 0 0 0 0 0 0 14.4014 -3.4780 0.0000 H 0 0 0 0 0 0 0 0 0 15.8565 -3.8470 0.0000 H 0 0 0 0 0 0 0 0 0 7.8059 -5.7498 0.0000 H 0 0 0 0 0 0 0 0 0 11.6778 -7.5945 0.0000 C 0 0 0 0 0 0 0 0 0 6.3882 -5.7498 0.0000 H 0 0 0 0 0 0 0 0 0 4 28 1 0 0 0 28 29 1 0 0 0 14 13 1 1 0 0 2 3 1 0 0 0 6 15 1 0 0 0 3 4 1 0 0 0 29 30 1 0 0 0 30 31 1 0 0 0 31 32 1 0 0 0 32 28 1 0 0 0 15 16 1 0 0 0 30 33 1 6 0 0 4 5 1 0 0 0 30 34 1 0 0 0 34 35 1 0 0 0 15 17 1 1 0 0 5 1 1 0 0 0 16 18 2 0 0 0 6 11 1 0 0 0 35 36 1 0 0 0 36 37 1 0 0 0 37 38 1 0 0 0 38 34 1 0 0 0 16 19 1 0 0 0 35 39 1 6 0 0 14 20 1 0 0 0 37 40 1 0 0 0 40 41 1 0 0 0 7 8 1 0 0 0 8 9 1 0 0 0 9 10 1 0 0 0 10 11 1 0 0 0 14 23 1 0 0 0 40 45 1 0 0 0 41 42 1 0 0 0 42 43 1 0 0 0 43 44 1 0 0 0 44 45 1 0 0 0 20 21 1 0 0 0 44 46 1 6 0 0 21 22 1 0 0 0 44 47 1 0 0 0 22 1 1 0 0 0 47 48 1 0 0 0 1 23 1 1 0 0 43 49 1 6 0 0 6 7 1 0 0 0 41 50 1 6 0 0 21 24 1 6 0 0 28 51 1 6 0 0 7 12 1 6 0 0 34 52 1 1 0 0 24 25 1 0 0 0 37 53 1 6 0 0 1 2 1 0 0 0 40 54 1 6 0 0 22 26 1 6 0 0 10 55 1 6 0 0 10 13 1 0 0 0 2 56 1 1 0 0 4 27 1 1 0 0 6 57 1 1 0 0 M END > CHEBI:7569 > nigericin > A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. > 3 > CHEBI:530451 > Polyetherin A; Helixin C; Azalomycin M > (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid > C40H68O11 > 724.96130 > 724.47616 > 0 > [H][C@@]1(CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C(O)=O)C[C@@H]1C[C@@H](OC)[C@@H](C)[C@]2(O1)O[C@@](C)(C[C@H]2C)[C@@]1([H])CC[C@](C)(O1)[C@]1([H])O[C@]([H])(C[C@@H]1C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C > InChI=1S/C40H68O11/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34/h21-35,41,44H,11-20H2,1-10H3,(H,42,43)/t21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35+,37-,38-,39-,40+/m0/s1 > DANUORFCFTYTSZ-SJSJOXFOSA-N > 74670 > 28380-24-7 > 74670 > 28380-24-7 > C11609 > C00018750 > Nigericin > 10341035; 10516103; 10996433; 15595852; 17618633; 20678563; 20709811; 20951746; 21257734; 22327078; 22493436; 7592045; 7638257; 7829226; 8010949; 8076364; 8717427; 8895841; 8913333; 9018148; 9178132; 9770325 $$$$