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M  END
> <ID>
CHEBI:90524

> <NAME>
PI-103

> <DEFINITION>
An organic heterotricyclic compound that is pyrido[3',2':4,5]furo[3,2-d]pyrimidine substituted at positions 2 and 4 by 3-hydroxyphenyl and morpholin-4-yl groups respectively. A dual-kinase inhibitor with anti-cancer properties.

> <STAR>
3

> <SYNONYM>
PIK-103; pi-103

> <IUPAC_NAME>
3-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol

> <FORMULA>
C19H16N4O3

> <MASS>
348.356

> <MONOISOTOPIC_MASS>
348.12224

> <CHARGE>
0

> <SMILES>
N=1C=CC=C2C1OC=3C2=NC(=NC3N4CCOCC4)C=5C=CC=C(O)C5

> <INCHI>
InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2

> <INCHIKEY>
TUVCWJQQGGETHL-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
371935-74-9

> <REAXYS_REGISTRY_NUMBER>
11065715

> <CHEMIDPLUS>
371935-74-9

> <LINCS_ACCESSION>
LSM-1126

> <PDBECHEM_ACCESSION>
X6K

> <PUBMED_CITATION>
20339072; 23636326; 24900786; 25575882; 25721419; 25884663; 26121251

$$$$