Ketcher 04282111492D 1   1.00000     0.00000     0

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 20 21  2  0     0  0
M  END
> <ID>
CHEBI:4601

> <NAME>
diloxanide furoate

> <DEFINITION>
A carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis.

> <STAR>
3

> <SYNONYM>
entamide furoate; diloxanide furoate; diloxanid furoate; CB 8073; 8073 CB

> <IUPAC_NAME>
4-[(dichloroacetyl)(methyl)amino]phenyl furan-2-carboxylate

> <BRAND_NAME>
Miforon; Histomibal; Furentomin; Furamide; Diclofurazol; Dichlofurazol; Amebiazol

> <FORMULA>
C14H11Cl2NO4

> <MASS>
328.150

> <MONOISOTOPIC_MASS>
327.00651

> <CHARGE>
0

> <SMILES>
CN(C(=O)C(Cl)Cl)C1=CC=C(OC(=O)C2=CC=CO2)C=C1

> <INCHI>
InChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3

> <INCHIKEY>
BDYYDXJSHYEDGB-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
3736-81-0

> <CHEMIDPLUS>
3736-81-0

> <DRUGBANK_ACCESSION>
DB14638

> <KEGG_COMPOUND_ACCESSION>
C07637

> <KEGG_DRUG_ACCESSION>
D02480

> <LINCS_ACCESSION>
LSM-2223

> <WIKIPEDIA_ACCESSION>
Diloxanide

> <PUBMED_CITATION>
10703963; 11411943; 11680811; 11929661; 14602387; 15081350; 1520794; 16055294; 16867415; 16867588; 18486369; 21394273; 2193407; 22165007; 23770637; 23807049; 26952868; 2874011; 28758845; 4350466; 8500812; 8713754; 9135682; 9178149

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