Ketcher 09261912462D 1 1.00000 0.00000 0 31 33 0 0 0 999 V2000 10.7426 -30.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7425 -29.5304 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6085 -29.0304 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4745 -29.5304 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3406 -29.0303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.2066 -29.5303 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 15.0742 -29.0330 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.2096 -30.5302 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0725 -28.0303 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 14.2065 -27.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.2065 -26.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.9385 -27.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3403 -28.0303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3403 -26.0303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0725 -26.0303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.9385 -26.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4744 -26.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4744 -27.5303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0725 -25.0303 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 11.6084 -26.0303 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.0103 -27.5306 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7424 -27.5304 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8764 -28.0305 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8762 -26.0305 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0103 -26.5306 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7423 -26.5304 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8765 -29.0305 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1441 -26.0306 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 16.8045 -28.0303 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.9394 -29.5345 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0764 -31.0289 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 3 2 1 0 0 0 4 3 1 0 0 0 5 4 1 0 0 0 6 5 1 0 0 0 7 6 1 0 0 0 8 6 1 0 0 0 10 9 2 0 0 0 12 9 1 0 0 0 11 10 1 0 0 0 13 10 1 0 0 0 14 11 1 0 0 0 15 11 2 0 0 0 16 12 2 0 0 0 29 12 1 0 0 0 18 13 2 0 0 0 17 14 2 0 0 0 16 15 1 0 0 0 19 15 1 0 0 0 18 17 1 0 0 0 20 17 1 0 0 0 26 20 1 0 0 0 23 21 2 0 0 0 25 21 1 0 0 0 23 22 1 0 0 0 26 22 2 0 0 0 27 23 1 0 0 0 25 24 2 0 0 0 26 24 1 0 0 0 28 25 1 0 0 0 2 27 1 0 0 0 7 30 1 0 0 0 8 31 1 0 0 0 M END > CHEBI:144984 > NSC 23766 > An aminopyrimidine that is 6-methylpyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 5-(diethylamino)pentan-2-yl and 4-amino-2-methylquinolin-6-yl groups respectively. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). > 3 > CHEBI:91883 > NSC23766; NSC-23766; N6-[2-[5-(diethylamino)pentan-2-ylamino]-6-methyl-4-pyrimidinyl]-2-methylquinoline-4,6-diamine > N(6)-(2-{[5-(diethylamino)pentan-2-yl]amino}-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine > C24H35N7 > 421.593 > 421.29539 > 0 > CC(CCCN(CC)CC)NC1=NC(=CC(NC2=CC=3C(=NC(=CC3N)C)C=C2)=N1)C > InChI=1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30) > DEFBCZWQLILOJF-UHFFFAOYSA-N > LSM-1818 > 15128949; 18183417; 19052208; 19491337; 20515940; 21511011; 23887096; 24257023; 24523909; 24953831; 25154784; 25319697; 25628054; 25631101; 27467102; 29050986; 30871916 $$$$