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M  END
> <ID>
CHEBI:143119

> <NAME>
N-(2-methoxyethyl)-4-{[6-(pyridin-4-yl)quinazolin-2-yl]amino}benzamide

> <DEFINITION>
A member of the class of quinazolines that is quinazoline which is substituted by a {4-[(2-methoxyethyl)carbamoyl]phenyl}nitrilo group and a pyridin-4-yl group at positions 2 and 6, respectively. It is a B-Raf and MKNK2 kinase inhibitor.

> <STAR>
3

> <SYNONYM>
UNC-BE1-004

> <IUPAC_NAME>
N-(2-methoxyethyl)-4-{[6-(pyridin-4-yl)quinazolin-2-yl]amino}benzamide

> <FORMULA>
C23H21N5O2

> <MASS>
399.454

> <MONOISOTOPIC_MASS>
399.16952

> <CHARGE>
0

> <SMILES>
O=C(C1=CC=C(NC2=NC3=CC=C(C4=CC=NC=C4)C=C3C=N2)C=C1)NCCOC

> <INCHI>
InChI=1S/C23H21N5O2/c1-30-13-12-25-22(29)17-2-5-20(6-3-17)27-23-26-15-19-14-18(4-7-21(19)28-23)16-8-10-24-11-9-16/h2-11,14-15H,12-13H2,1H3,(H,25,29)(H,26,27,28)

> <INCHIKEY>
NXVFABZXYFFUBF-UHFFFAOYSA-N

> <PDBECHEM_ACCESSION>
32W

> <PUBMED_CITATION>
23398453

$$$$