Ketcher 07052410592D 1   1.00000     0.00000     0

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 22 28  1  0     0  0
M  END
> <ID>
CHEBI:95003

> <NAME>
MST-312

> <DEFINITION>
A member of the class of benzamides that results from the formal condensation of the two amino groups of benzene-1,3-diamine with the carboxylic acid groups of two molar equivalents of 2,3-dihydroxybenzoic acid. It is telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay) and exhibits antineoplastic activity.

> <STAR>
3

> <SYNONYM>
telomerase inhibitor IX; N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide; N,N'-bis(2,3-dihydroxybenzoyl)-1,3-phenylenediamine; N,N'-(1,3-phenylene)bis(2,3-dihydroxybenzamide); MST312; MST 312

> <IUPAC_NAME>
N,N'-benzene-1,3-diylbis(2,3-dihydroxybenzamide)

> <FORMULA>
C20H16N2O6

> <MASS>
380.356

> <MONOISOTOPIC_MASS>
380.10084

> <CHARGE>
0

> <SMILES>
OC1=CC=CC(C(=O)NC2=CC(NC(=O)C3=C(O)C(O)=CC=C3)=CC=C2)=C1O

> <INCHI>
InChI=1S/C20H16N2O6/c23-15-8-2-6-13(17(15)25)19(27)21-11-4-1-5-12(10-11)22-20(28)14-7-3-9-16(24)18(14)26/h1-10,23-26H,(H,21,27)(H,22,28)

> <INCHIKEY>
MIQUEZGHEJGPJB-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
368449-04-1

> <LINCS_ACCESSION>
LSM-6230

> <PUBMED_CITATION>
12479362; 25596016; 26022158; 26022559; 26178994; 27279256; 28520570; 29604359; 30170357; 31012504; 31029779; 31921617; 33922244; 34957975; 35809296; 35811464; 36274541; 36378860; 38216120; 38252348; 38765717

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