Mrv0541 11151311552D          

 22 24  0  0  0  0            999 V2000
    3.3635   -0.7652    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0755   -1.1778    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0755   -2.0027    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.3635   -2.4153    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    2.6474   -1.1778    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6498   -2.0045    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8643   -2.2623    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3765   -1.5948    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8604   -0.9246    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    4.7902   -0.7658    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7910    0.0592    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.5045   -1.1788    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    6.2193   -0.7668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.2187    0.0553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9335    0.4673    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6476    0.0543    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.6470   -0.7707    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.9323   -1.1828    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.7902   -2.4147    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3645    0.0598    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9511   -3.1297    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.7760   -3.1297    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  5  1  1  0  0  0  0
  1  2  2  0  0  0  0
  2 10  1  0  0  0  0
  2  3  1  0  0  0  0
 10 11  2  0  0  0  0
  3  4  1  0  0  0  0
 10 12  1  0  0  0  0
  5  6  2  0  0  0  0
 12 13  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9  5  1  0  0  0  0
  4  6  1  0  0  0  0
 13 14  2  0  0  0  0
 14 15  1  0  0  0  0
 15 16  2  0  0  0  0
 16 17  1  0  0  0  0
 17 18  2  0  0  0  0
 18 13  1  0  0  0  0
  3 19  1  0  0  0  0
  1 20  1  0  0  0  0
  4 21  2  0  0  0  0
 22  4  2  0  0  0  0
M  END
> <ID>
CHEBI:32192

> <NAME>
tenoxicam

> <DEFINITION>
A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine.  Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries.

> <STAR>
3

> <IUPAC_NAME>
4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

> <INN>
tenoxicamum; tenoxicam; tenoxicam; tenoxicam

> <BRAND_NAME>
Tilcotil; Mobiflex

> <FORMULA>
C13H11N3O4S2

> <MASS>
337.37400

> <MONOISOTOPIC_MASS>
337.01910

> <CHARGE>
0

> <SMILES>
CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O

> <INCHI>
InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)

> <INCHIKEY>
LZNWYQJJBLGYLT-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
59804-37-4

> <REAXYS_REGISTRY_NUMBER>
572193

> <CHEMIDPLUS>
59804-37-4

> <DRUGBANK_ACCESSION>
DB00469

> <KEGG_DRUG_ACCESSION>
D01767

> <WIKIPEDIA_ACCESSION>
Tenoxicam

> <PUBMED_CITATION>
21129461; 21327813; 21682312; 21712619; 21777594; 21929527; 21981557; 22095696; 22182582; 22306394; 22675955; 22841852; 22876956; 23204620; 23273940; 23340327; 23480456; 23656309; 23932198; 24037655; 24093711; 28166217

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