Mrv0541 07211416052D 34 37 0 0 0 0 999 V2000 -1.3820 -6.5892 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3820 -7.4142 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0965 -6.1767 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0965 -7.8267 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.8110 -6.5892 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8110 -7.4142 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6675 -7.8267 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.5254 -7.8267 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.2399 -7.4142 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9544 -7.8267 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2399 -6.5892 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6689 -7.4141 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9544 -6.1767 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6688 -6.5892 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9544 -8.6517 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.5254 -6.1767 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 0.0470 -7.4143 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0470 -6.5893 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7615 -7.8268 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7615 -6.1768 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4759 -7.4143 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4760 -6.5893 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1905 -6.1768 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1905 -5.3518 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9050 -6.5894 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9051 -4.9394 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6194 -6.1769 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6195 -5.3519 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7615 -8.6518 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0470 -9.0643 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6689 -9.0642 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 -6.3834 -8.6517 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0814 -9.7787 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.2564 -9.7787 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 3 1 2 0 0 0 0 4 2 2 0 0 0 0 5 3 1 0 0 0 0 6 4 1 0 0 0 0 6 5 2 0 0 0 0 2 7 1 0 0 0 0 6 8 1 0 0 0 0 10 9 1 0 0 0 0 11 9 2 0 0 0 0 12 10 2 0 0 0 0 13 11 1 0 0 0 0 14 12 1 0 0 0 0 14 13 2 0 0 0 0 8 9 1 0 0 0 0 10 15 1 0 0 0 0 5 16 1 0 0 0 0 18 17 1 0 0 0 0 19 17 2 0 0 0 0 20 18 2 0 0 0 0 21 19 1 0 0 0 0 22 20 1 0 0 0 0 22 21 2 0 0 0 0 7 17 1 0 0 0 0 24 23 1 0 0 0 0 25 23 1 0 0 0 0 26 24 1 0 0 0 0 27 25 1 0 0 0 0 28 26 1 0 0 0 0 28 27 1 0 0 0 0 22 23 1 0 0 0 0 19 29 1 0 0 0 0 29 30 1 0 0 0 0 15 31 1 0 0 0 0 31 32 1 0 0 0 0 31 33 2 0 0 0 0 31 34 2 0 0 0 0 M END > CHEBI:78414 > CZC-25146 > A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. > 3 > N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide > C22H25ClN6O4S > 504.99000 > 504.13465 > 0 > COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1 > InChI=1S/C22H25ClN6O4S/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27) > CLGWUCNXOBLWFM-UHFFFAOYSA-N > 19687577 > 21812418; 24725412 $$$$