CHEBI:33191 - potassium cyanide

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ChEBI Name potassium cyanide
ChEBI ID CHEBI:33191
Definition A cyanide salt containing equal numbers of potassium cations and cyanide anions.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB62497938, eMolecules:514516
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Potassium cyanide is a compound with the formula KCN. It is a colorless salt, similar in appearance to sugar, that is highly soluble in water. Most KCN is used in gold mining, organic synthesis, and electroplating. Smaller applications include jewellery for chemical gilding and buffing. Potassium cyanide is highly toxic, and a dose of 200 to 300 milligrams will kill nearly any human. The moist solid emits small amounts of hydrogen cyanide due to hydrolysis (reaction with water). Hydrogen cyanide is often described as having an odor resembling that of bitter almonds. The taste of potassium cyanide has been described as acrid and bitter, with a burning sensation similar to lye.
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Formula CKN
Net Charge 0
Average Mass 65.116
Monoisotopic Mass 64.96678
InChI InChI=1S/CN.K/c1-2;/q-1;+1
InChIKey NNFCIKHAZHQZJG-UHFFFAOYSA-N
SMILES [C-]#N.[K+]
Roles Classification
Biological Role(s): EC 1.9.3.1 (cytochrome c oxidase) inhibitor
An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).
EC 1.15.1.1 (superoxide dismutase) inhibitor
An EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitor that interferes with the action of superoxide dismutase (EC 1.15.1.1).
neurotoxin
A poison that interferes with the functions of the nervous system.
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ChEBI Ontology
Outgoing potassium cyanide (CHEBI:33191) has role EC 1.15.1.1 (superoxide dismutase) inhibitor (CHEBI:134084)
potassium cyanide (CHEBI:33191) has role EC 1.9.3.1 (cytochrome c oxidase) inhibitor (CHEBI:38500)
potassium cyanide (CHEBI:33191) has role neurotoxin (CHEBI:50910)
potassium cyanide (CHEBI:33191) is a cyanide salt (CHEBI:36572)
potassium cyanide (CHEBI:33191) is a one-carbon compound (CHEBI:64708)
potassium cyanide (CHEBI:33191) is a potassium salt (CHEBI:26218)
IUPAC Name
potassium cyanide
Synonyms Sources
cyanide of potassium NIST Chemistry WebBook
Kaliumcyanid ChEBI
Kaliumzyanid ChEBI
KCN IUPAC
Zyankali ChEBI
Manual Xref Database
Potassium_cyanide Wikipedia
View more database links
Registry Numbers Types Sources
151-50-8 CAS Registry Number ChemIDplus
151-50-8 CAS Registry Number NIST Chemistry WebBook
3593645 Beilstein Registry Number Beilstein
4652394 Beilstein Registry Number ChemIDplus
647425 Gmelin Registry Number Gmelin
Citations
Batista LA, Haibara AS, Schenberg LC, Moreira FA (2017)
Effects of alprazolam and cannabinoid-related compounds in an animal model of panic attack.
Behavioural brain research 317, 508-514 [PubMed:27737792]
[show Abstract]
Hawk MA, Ritchie GD, Henderson KA, Knostman KA, Roche BM, Ma ZJ, Matthews CM, Sabourin CL, Wakayama EJ, Sabourin PJ (2016)
Neurobehavioral and Cardiovascular Effects of Potassium Cyanide Administered Orally to Mice.
International journal of toxicology 35, 604-615 [PubMed:27170681]
[show Abstract]
Sabourin PJ, Kobs CL, Gibbs ST, Hong P, Matthews CM, Patton KM, Sabourin CL, Wakayama EJ (2016)
Characterization of a Mouse Model of Oral Potassium Cyanide Intoxication.
International journal of toxicology 35, 584-603 [PubMed:27170682]
[show Abstract]
Fang D, Qing Y, Yan S, Chen D, Yan SS (2016)
Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs.
Stem cell reports 7, 678-692 [PubMed:27666790]
[show Abstract]
Kumano T, Takizawa Y, Shimizu S, Kobayashi M (2016)
Nitrile-synthesizing enzyme: Gene cloning, overexpression and application for the production of useful compounds.
The Journal of general and applied microbiology 62, 174-180 [PubMed:27250664]
[show Abstract]
Lee JH, Jang JH, Velusamy N, Jung HS, Bhuniya S, Kim JS (2015)
An intramolecular crossed-benzoin reaction based KCN fluorescent probe in aqueous and biological environments.
Chemical communications (Cambridge, England) 51, 7709-7712 [PubMed:25850896]
[show Abstract]
Yamagiwa T, Inokuchi S, Saito T, Inoue S, Morita S, Kawaguchi AT (2013)
A stable in vitro method for assessing the toxicity of potassium cyanide and its antidote.
The Tokai journal of experimental and clinical medicine 38, 114-122 [PubMed:24318282]
[show Abstract]
Dairam A, Chetty P, Daya S (2006)
Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons.
Metabolic brain disease 21, 221-233 [PubMed:16850258]
[show Abstract]
Last Modified
07 December 2016