CHEBI:17984 - acyl-CoA

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name acyl-CoA
ChEBI ID CHEBI:17984
Definition A thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:13802, CHEBI:2455, CHEBI:13727, CHEBI:22223
Download Molfile XML SDF
Formulae C22H35N7O17P3RS
C22H35N7O17P3SR
Net Charge 0
Average Mass (excl. R groups) 794.53600
Monoisotopic Mass (excl. R groups) 794.10230
SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC([*])=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Roles Classification
Chemical Role(s): acyl donor
Any donor that can transfer acyl groups between molecular entities.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing acyl-CoA (CHEBI:17984) has functional parent coenzyme A (CHEBI:15346)
acyl-CoA (CHEBI:17984) has role acyl donor (CHEBI:62049)
acyl-CoA (CHEBI:17984) is a 6-aminopurines (CHEBI:20706)
acyl-CoA (CHEBI:17984) is a nucleotide derivative (CHEBI:231540)
acyl-CoA (CHEBI:17984) is a secondary carboxamide (CHEBI:140325)
acyl-CoA (CHEBI:17984) is a thioester (CHEBI:51277)
acyl-CoA (CHEBI:17984) is conjugate acid of acyl-CoA(4−) (CHEBI:58342)
Incoming β-alanyl-CoA (CHEBI:15507) is a acyl-CoA (CHEBI:17984)
γ-butyrobetainyl-CoA (CHEBI:61517) is a acyl-CoA (CHEBI:17984)
ω-carboxyacyl-CoA (CHEBI:37555) is a acyl-CoA (CHEBI:17984)
(2,3,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA (CHEBI:27866) is a acyl-CoA (CHEBI:17984)
(2E)-hexadecenedioyl-CoA (CHEBI:77183) is a acyl-CoA (CHEBI:17984)
(2E)-tetradecenedioyl-CoA (CHEBI:77170) is a acyl-CoA (CHEBI:17984)
(2S)-methylsuccinyl-CoA (CHEBI:81672) is a acyl-CoA (CHEBI:17984)
(2Z)-4-carboxy-2-sulfanylbut-2-enoyl-CoA (CHEBI:71243) is a acyl-CoA (CHEBI:17984)
(3R)-3-amino-3-phenylpropanoyl-CoA (CHEBI:83170) is a acyl-CoA (CHEBI:17984)
(4-coumaroyl)acetyl-CoA (CHEBI:71215) is a acyl-CoA (CHEBI:17984)
(E)-2-benzylidenesuccinyl-CoA (CHEBI:27639) is a acyl-CoA (CHEBI:17984)
(E)-4-(trimethylammonio)but-2-enoyl-CoA (CHEBI:61123) is a acyl-CoA (CHEBI:17984)
(R)-phenyllactoyl-CoA (CHEBI:11010) is a acyl-CoA (CHEBI:17984)
(S)-2-benzoylsuccinyl-CoA (CHEBI:28882) is a acyl-CoA (CHEBI:17984)
1,4-dihydroxy-2-naphthoyl-CoA (CHEBI:52668) is a acyl-CoA (CHEBI:17984)
2,3-epoxy-2,3-dihydrobenzoyl-CoA (CHEBI:90162) is a acyl-CoA (CHEBI:17984)
2,5-dihydroxybenzoyl-CoA (CHEBI:90176) is a acyl-CoA (CHEBI:17984)
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA (CHEBI:63547) is a acyl-CoA (CHEBI:17984)
2-amino-5-oxocyclohex-1-enecarbonyl-CoA (CHEBI:18206) is a acyl-CoA (CHEBI:17984)
2-aminobenzoylacetyl-CoA (CHEBI:131952) is a acyl-CoA (CHEBI:17984)
2-carboxyacyl-CoA (CHEBI:84127) is a acyl-CoA (CHEBI:17984)
2-furoyl-CoA (CHEBI:15474) is a acyl-CoA (CHEBI:17984)
2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA (CHEBI:79293) is a acyl-CoA (CHEBI:17984)
2-naphthoyl-CoA (CHEBI:34300) is a acyl-CoA (CHEBI:17984)
2-oxepin-2(3H)-ylideneacetyl-CoA (CHEBI:63251) is a acyl-CoA (CHEBI:17984)
2-oxoglutaryl-CoA (CHEBI:71364) is a acyl-CoA (CHEBI:17984)
3,5-dihydroxyphenylacetyl-CoA (CHEBI:31103) is a acyl-CoA (CHEBI:17984)
3,8-dioxooct-5-enoyl-CoA (CHEBI:63256) is a acyl-CoA (CHEBI:17984)
3-(4-hydroxy-3-methoxyphenyl)-3-oxopropanoyl-CoA (CHEBI:142889) is a acyl-CoA (CHEBI:17984)
3-(m-hydroxyphenyl)propanoyl-CoA (CHEBI:87996) is a acyl-CoA (CHEBI:17984)
3-(methylthio)acryloyl-CoA (CHEBI:85528) is a acyl-CoA (CHEBI:17984)
3-(methylthio)propanoyl-CoA (CHEBI:83579) is a acyl-CoA (CHEBI:17984)
3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoyl-CoA (CHEBI:84601) is a acyl-CoA (CHEBI:17984)
3-[({2-[(3-{[4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-1,2-dihydroxy-3,3-dimethylbutylidene]amino}-1-hydroxypropylidene)amino]ethyl}sulfanyl)carbonyl]-4-hydroxy-4-phenylbutanoic acid (CHEBI:184474) is a acyl-CoA (CHEBI:17984)
3-dehydrocarnityl CoA (CHEBI:85886) is a acyl-CoA (CHEBI:17984)
3-hydroxy-3-(methylthio)propanoyl-CoA (CHEBI:85529) is a acyl-CoA (CHEBI:17984)
3-isopropenylpimeloyl-CoA (CHEBI:37439) is a acyl-CoA (CHEBI:17984)
3-oxo-5,6-dehydrosuberyl-CoA (CHEBI:63253) is a acyl-CoA (CHEBI:17984)
3-oxo-8-carboxy-5-octenoyl-CoA (CHEBI:186430) is a acyl-CoA (CHEBI:17984)
3-oxodecanedioyl-CoA (CHEBI:76445) is a acyl-CoA (CHEBI:17984)
3-oxododecanedioyl-CoA (CHEBI:76439) is a acyl-CoA (CHEBI:17984)
3-oxohexadecanedioyl-CoA (CHEBI:77191) is a acyl-CoA (CHEBI:17984)
3-oxooctanedioyl-CoA (CHEBI:76426) is a acyl-CoA (CHEBI:17984)
3-Oxopimelyl-CoA (CHEBI:172855) is a acyl-CoA (CHEBI:17984)
3-oxotetradecanedioyl-CoA (CHEBI:77172) is a acyl-CoA (CHEBI:17984)
3-phenylpropanoyl-CoA (CHEBI:85675) is a acyl-CoA (CHEBI:17984)
3-substituted propionyl-CoA (CHEBI:65122) is a acyl-CoA (CHEBI:17984)
3-sulfinopropionyl-CoA (CHEBI:79221) is a acyl-CoA (CHEBI:17984)
4-(2-carboxyphenyl)-4-oxobutanoyl-CoA (CHEBI:15509) is a acyl-CoA (CHEBI:17984)
4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-2-hydroxy-N-{2-[(2-{[2-(4-hydroxyphenyl)acetyl]sulfanyl}ethyl)-C-hydroxycarbonimidoyl]ethyl}-3,3-dimethylbutanimidic acid (CHEBI:185055) is a acyl-CoA (CHEBI:17984)
4-acetamidobutanoyl-CoA (CHEBI:28684) is a acyl-CoA (CHEBI:17984)
4-carboxy-2-thioxobutanoyl-CoA (CHEBI:71313) is a acyl-CoA (CHEBI:17984)
4-isopropenyl-2-oxocyclohexane-1-carbonyl-CoA (CHEBI:29489) is a acyl-CoA (CHEBI:17984)
5-hydroxy-2-furoyl-CoA (CHEBI:15510) is a acyl-CoA (CHEBI:17984)
5-hydroxyferuloyl-CoA (CHEBI:31136) is a acyl-CoA (CHEBI:17984)
5-hydroxythiophene-2-carbonyl-CoA (CHEBI:15502) is a acyl-CoA (CHEBI:17984)
5-oxo-furan-2-acetyl-CoA (CHEBI:49304) is a acyl-CoA (CHEBI:17984)
9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oyl-CoA (CHEBI:79246) is a acyl-CoA (CHEBI:17984)
N,N,N-trimethylglycyl-CoA (CHEBI:85888) is a acyl-CoA (CHEBI:17984)
trans-2,3-didehydroadipoyl-CoA (CHEBI:49295) is a acyl-CoA (CHEBI:17984)
trans-2-decenedioyl-CoA (CHEBI:76443) is a acyl-CoA (CHEBI:17984)
trans-2-dodecenedioyl-CoA (CHEBI:76427) is a acyl-CoA (CHEBI:17984)
trans-2-octenedioyl-CoA (CHEBI:76423) is a acyl-CoA (CHEBI:17984)
L-cysteine coenzyme A disulfide (CHEBI:21263) is a acyl-CoA (CHEBI:17984)
L-firefly luciferyl-CoA (CHEBI:139035) is a acyl-CoA (CHEBI:17984)
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA (CHEBI:64900) is a acyl-CoA (CHEBI:17984)
[(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA (CHEBI:64819) is a acyl-CoA (CHEBI:17984)
Acetyl coenzyme A (Acetyl-CoA) (CHEBI:180918) is a acyl-CoA (CHEBI:17984)
acetyl-CoA (CHEBI:15351) is a acyl-CoA (CHEBI:17984)
aroyl-CoA (CHEBI:61940) is a acyl-CoA (CHEBI:17984)
ascr#1-CoA (CHEBI:139645) is a acyl-CoA (CHEBI:17984)
ascr#10-CoA (CHEBI:139616) is a acyl-CoA (CHEBI:17984)
ascr#21-CoA (CHEBI:139651) is a acyl-CoA (CHEBI:17984)
ascr#22-CoA (CHEBI:139654) is a acyl-CoA (CHEBI:17984)
ascr#3-CoA (CHEBI:139705) is a acyl-CoA (CHEBI:17984)
ascr#7-CoA (CHEBI:139711) is a acyl-CoA (CHEBI:17984)
benzoylacetyl-CoA (CHEBI:27388) is a acyl-CoA (CHEBI:17984)
biotinyl-CoA (CHEBI:15516) is a acyl-CoA (CHEBI:17984)
bkos#9-CoA (CHEBI:139962) is a acyl-CoA (CHEBI:17984)
caffeoyl-CoA (CHEBI:15518) is a acyl-CoA (CHEBI:17984)
cinnamoyl-CoA (CHEBI:15463) is a acyl-CoA (CHEBI:17984)
cinnamoyl-CoAs (CHEBI:23253) is a acyl-CoA (CHEBI:17984)
CoA(12:0(3Ke)) (CHEBI:165616) is a acyl-CoA (CHEBI:17984)
cyclohex-1-ene-1-carbonyl-CoA (CHEBI:28005) is a acyl-CoA (CHEBI:17984)
cyclohexa-1,4-diene-1-carbonyl-CoA (CHEBI:28443) is a acyl-CoA (CHEBI:17984)
cyclohexa-2,5-diene-1-carbonyl-CoA (CHEBI:27610) is a acyl-CoA (CHEBI:17984)
cyclohexane-1-carbonyl-CoA (CHEBI:28557) is a acyl-CoA (CHEBI:17984)
dihydrocaffeoyl-CoA (CHEBI:87451) is a acyl-CoA (CHEBI:17984)
fatty acyl-CoA (CHEBI:37554) is a acyl-CoA (CHEBI:17984)
feruloyl-CoA (CHEBI:14261) is a acyl-CoA (CHEBI:17984)
feruloylacetyl-CoA (CHEBI:71236) is a acyl-CoA (CHEBI:17984)
formyl-CoA (CHEBI:15522) is a acyl-CoA (CHEBI:17984)
haloacyl-CoA (CHEBI:62048) is a acyl-CoA (CHEBI:17984)
hexadecanedioyl-CoA (CHEBI:77208) is a acyl-CoA (CHEBI:17984)
hydroxyacyl-CoA (CHEBI:62618) is a acyl-CoA (CHEBI:17984)
indol-3-ylacetyl-CoA (CHEBI:12755) is a acyl-CoA (CHEBI:17984)
malonamoyl-CoA (CHEBI:28334) is a acyl-CoA (CHEBI:17984)
malonyl-CoA methyl ester (CHEBI:71244) is a acyl-CoA (CHEBI:17984)
Malonyl-CoA semialdehyde (CHEBI:177266) is a acyl-CoA (CHEBI:17984)
malonyl-CoAs (CHEBI:25136) is a acyl-CoA (CHEBI:17984)
methacrylyl-CoA (CHEBI:27754) is a acyl-CoA (CHEBI:17984)
mevalonyl-CoA (CHEBI:133868) is a acyl-CoA (CHEBI:17984)
oscr#1-CoA (CHEBI:139993) is a acyl-CoA (CHEBI:17984)
oscr#10-CoA (CHEBI:139966) is a acyl-CoA (CHEBI:17984)
oscr#12-CoA (CHEBI:139969) is a acyl-CoA (CHEBI:17984)
oscr#13-CoA (CHEBI:139973) is a acyl-CoA (CHEBI:17984)
oscr#14-CoA (CHEBI:139976) is a acyl-CoA (CHEBI:17984)
oscr#15-CoA (CHEBI:139979) is a acyl-CoA (CHEBI:17984)
oscr#16-CoA (CHEBI:139982) is a acyl-CoA (CHEBI:17984)
oscr#17-CoA (CHEBI:139985) is a acyl-CoA (CHEBI:17984)
oscr#18-CoA (CHEBI:139988) is a acyl-CoA (CHEBI:17984)
oscr#19-CoA (CHEBI:139991) is a acyl-CoA (CHEBI:17984)
oscr#20-CoA (CHEBI:139996) is a acyl-CoA (CHEBI:17984)
oscr#21-CoA (CHEBI:139999) is a acyl-CoA (CHEBI:17984)
oscr#22-CoA (CHEBI:140002) is a acyl-CoA (CHEBI:17984)
oscr#23-CoA (CHEBI:140005) is a acyl-CoA (CHEBI:17984)
oscr#24-CoA (CHEBI:140008) is a acyl-CoA (CHEBI:17984)
oscr#25-CoA (CHEBI:140011) is a acyl-CoA (CHEBI:17984)
oscr#26-CoA (CHEBI:140014) is a acyl-CoA (CHEBI:17984)
oscr#27-CoA (CHEBI:140017) is a acyl-CoA (CHEBI:17984)
oscr#28-CoA (CHEBI:140020) is a acyl-CoA (CHEBI:17984)
oscr#29-CoA (CHEBI:140023) is a acyl-CoA (CHEBI:17984)
oscr#3-CoA (CHEBI:140053) is a acyl-CoA (CHEBI:17984)
oscr#30-CoA (CHEBI:140027) is a acyl-CoA (CHEBI:17984)
oscr#31-CoA (CHEBI:140030) is a acyl-CoA (CHEBI:17984)
oscr#32-CoA (CHEBI:140033) is a acyl-CoA (CHEBI:17984)
oscr#33-CoA (CHEBI:140036) is a acyl-CoA (CHEBI:17984)
oscr#34-CoA (CHEBI:140039) is a acyl-CoA (CHEBI:17984)
oscr#35-CoA (CHEBI:140042) is a acyl-CoA (CHEBI:17984)
oscr#36-CoA (CHEBI:140045) is a acyl-CoA (CHEBI:17984)
oscr#37-CoA (CHEBI:140048) is a acyl-CoA (CHEBI:17984)
oscr#38-CoA (CHEBI:140051) is a acyl-CoA (CHEBI:17984)
oscr#7-CoA (CHEBI:140056) is a acyl-CoA (CHEBI:17984)
oscr#9-CoA (CHEBI:140059) is a acyl-CoA (CHEBI:17984)
perillyl-coenzyme A (CHEBI:37002) is a acyl-CoA (CHEBI:17984)
phenoxyacetyl-CoA (CHEBI:28964) is a acyl-CoA (CHEBI:17984)
phenylacetyl-CoA (CHEBI:15537) is a acyl-CoA (CHEBI:17984)
phenylacetyl-CoAs (CHEBI:25981) is a acyl-CoA (CHEBI:17984)
phenylglyoxylyl-CoA (CHEBI:50117) is a acyl-CoA (CHEBI:17984)
phytanoyl-CoAs (CHEBI:26114) is a acyl-CoA (CHEBI:17984)
pimeloyl-CoAs (CHEBI:26132) is a acyl-CoA (CHEBI:17984)
propenoyl-CoA (CHEBI:26302) is a acyl-CoA (CHEBI:17984)
propionyl-CoA (CHEBI:15539) is a acyl-CoA (CHEBI:17984)
Salicyl-CoA (CHEBI:165618) is a acyl-CoA (CHEBI:17984)
steroidal acyl-CoA (CHEBI:52135) is a acyl-CoA (CHEBI:17984)
sulfoacetyl-CoA (CHEBI:61992) is a acyl-CoA (CHEBI:17984)
tetradecanedioyl-CoA (CHEBI:77207) is a acyl-CoA (CHEBI:17984)
thiophene-2-carbonyl-CoA (CHEBI:15542) is a acyl-CoA (CHEBI:17984)
tinapoyl-CoA (CHEBI:27009) is a acyl-CoA (CHEBI:17984)
acyl-CoA(4−) (CHEBI:58342) is conjugate base of acyl-CoA (CHEBI:17984)
Synonyms Sources
Acyl coenzyme A KEGG COMPOUND
Acyl-CoA KEGG COMPOUND
Manual Xref Database
C00040 KEGG COMPOUND
View more database links
Citations
Hostetler HA, Lupas D, Tan Y, Dai J, Kelzer MS, Martin GG, Woldegiorgis G, Kier AB, Schroeder F (2011)
Acyl-CoA binding proteins interact with the acyl-CoA binding domain of mitochondrial carnitine palmitoyl transferase I.
Molecular and cellular biochemistry 355, 135-148 [PubMed:21541677]
[show Abstract]
Kim JH, Ee SM, Jittiwat J, Ong ES, Farooqui AA, Jenner AM, Ong WY (2011)
Increased expression of acyl-coenzyme A: cholesterol acyltransferase-1 and elevated cholesteryl esters in the hippocampus after excitotoxic injury.
Neuroscience 185, 125-134 [PubMed:21514367]
[show Abstract]
Ioriya K, Kino K, Horisawa S, Nishimura T, Muraoka M, Noguchi T, Ohashi N (2006)
Pharmacological profile of SMP-797, a novel acyl-coenzyme a: cholesterol acyltransferase inhibitor with inducible effect on the expression of low-density lipoprotein receptor.
Journal of cardiovascular pharmacology 47, 322-329 [PubMed:16495773]
[show Abstract]
Rudel LL, Lee RG, Cockman TL (2001)
Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis.
Current opinion in lipidology 12, 121-127 [PubMed:11264983]
[show Abstract]
Gregersen N, Andresen BS, Corydon MJ, Corydon TJ, Olsen RK, Bolund L, Bross P (2001)
Mutation analysis in mitochondrial fatty acid oxidation defects: Exemplified by acyl-CoA dehydrogenase deficiencies, with special focus on genotype-phenotype relationship.
Human mutation 18, 169-189 [PubMed:11524729]
[show Abstract]
Last Modified
06 June 2024