Aspartame is an artificial non-saccharide sweetener commonly used as a sugar substitute in foods and beverages. 200 times sweeter than sucrose, it is a methyl ester of the aspartic acid/phenylalanine dipeptide with brand names NutraSweet, Equal, and Canderel. Discovered in 1965, aspartame was approved by the US Food and Drug Administration (FDA) in 1974 and re-approved in 1981 after its initial approval was briefly revoked.
Aspartame is one of the most studied food additives in the human food supply. Reviews by over 100 governmental regulatory bodies found the ingredient safe for consumption at the normal acceptable daily intake limit. |
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InChI=1S/C16H26N2O5S/c1- 16(2) 8- 10(16) 13(19) 18- 12(15(22) 23) 6- 4- 3- 5- 7- 24- 9- 11(17) 14(20) 21/h6,10- 11H,3- 5,7- 9,17H2,1- 2H3,(H,18,19) (H,20,21) (H,22,23) /b12- 6- /t10- ,11+/m1/s1 |
DHSUYTOATWAVLW-WFVMDLQDSA-N |
CC1(C)C[C@@H]1C(=O)N\C(C(O)=O)=C/CCCCSC[C@H](N)C(O)=O |
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environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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EC 3.4.13.19 (membrane dipeptidase) inhibitor
An EC 3.4.13.* (dipeptidase) inhibitor that interferes with the action of membrane dipeptidase (EC 3.4.13.19).
protease inhibitor
A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
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View more via ChEBI Ontology
(2Z)- 7- {[(2R)- 2- amino- 2- carboxyethyl]sulfanyl}- 2- ({[(1S)- 2,2- dimethylcyclopropyl]carbonyl}amino)hept- 2- enoic acid
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cilastatin
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ChemIDplus
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cilastatina
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ChemIDplus
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cilastatine
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ChemIDplus
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cilastatinum
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ChemIDplus
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(L)- 7- (2- Amino- 2- carboxy- ethylsulfanyl)- 2- [(2,2- dimethyl- cyclopropanecarbonyl)- amino]- hept- 2- enoic acid
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ChEMBL
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(Z)- (S)- 6- carboxy- 6- [(S)- 2,2- dimethylcyclopropanecarboxamido]hex- 5- enyl- L- cysteine
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ChEBI
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(Z)- 7- ((R)- 2- Amino- 2- carboxy- ethylsulfanyl)- 2- [((S)- 2,2- dimethyl- cyclopropanecarbonyl)- amino]- hept- 2- enoic acid
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ChEMBL
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640
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DrugCentral
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C01675
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KEGG COMPOUND
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CIL
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PDBeChem
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Cilastatin
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Wikipedia
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D07698
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KEGG DRUG
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DB01597
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DrugBank
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EP48025
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Patent
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EP48301
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Patent
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EP72014
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Patent
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View more database links |
6895069
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Reaxys Registry Number
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Reaxys
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82009-34-5
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CAS Registry Number
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KEGG COMPOUND
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82009-34-5
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CAS Registry Number
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ChemIDplus
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3495664
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PubMed citation
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ChEMBL
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