Aspartame is an artificial non-saccharide sweetener commonly used as a sugar substitute in foods and beverages. 200 times sweeter than sucrose, it is a methyl ester of the aspartic acid/phenylalanine dipeptide with brand names NutraSweet, Equal, and Canderel. Discovered in 1965, aspartame was approved by the US Food and Drug Administration (FDA) in 1974 and re-approved in 1981 after its initial approval was briefly revoked.
Aspartame is one of the most studied food additives in the human food supply. Reviews by over 100 governmental regulatory bodies found the ingredient safe for consumption at the normal acceptable daily intake limit. |
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NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl |
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environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
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loop diuretic
A diuretic that acts on the ascending loop of Henle in the kidney.
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View more via ChEBI Ontology
4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
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2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
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ChemIDplus
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4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid
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ChemIDplus
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4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
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ChemIDplus
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4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
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ChemIDplus
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Frusemide
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KEGG DRUG
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Furosemide
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KEGG DRUG
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Lasix (TN)
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KEGG DRUG
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1399731
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Reaxys Registry Number
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Reaxys
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54-31-9
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CAS Registry Number
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ChemIDplus
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54-31-9
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CAS Registry Number
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KEGG DRUG
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15286542
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PubMed citation
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Europe PMC
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18701232
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PubMed citation
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Europe PMC
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