phorbol ester |
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CHEBI:37532 |
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Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C. |
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This entity has been manually annotated by the ChEBI Team.
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Outgoing
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phorbol ester
(CHEBI:37532)
has functional parent
phorbol
(CHEBI:8116)
phorbol ester
(CHEBI:37532)
is a
carboxylic ester
(CHEBI:33308)
phorbol ester
(CHEBI:37532)
is a
diterpenoid
(CHEBI:23849)
phorbol ester
(CHEBI:37532)
is a
tetracyclic diterpenoid
(CHEBI:52557)
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Incoming
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12-deoxyphorbaldehyde-13-hexadecanoate
(CHEBI:69821)
is a
phorbol ester
(CHEBI:37532)
12-deoxyphorbol 20-acetate 13-(2-methylbutanoate)
(CHEBI:4660)
is a
phorbol ester
(CHEBI:37532)
12-deoxyphorbol-13,20-diacetate
(CHEBI:69819)
is a
phorbol ester
(CHEBI:37532)
12-deoxyphorbol-13-(3E,5E-decadienoate)
(CHEBI:65747)
is a
phorbol ester
(CHEBI:37532)
12-deoxyphorbol-13-hexadecanoate
(CHEBI:69820)
is a
phorbol ester
(CHEBI:37532)
12-O-Decanoylphorbol-13-acetate
(CHEBI:70537)
is a
phorbol ester
(CHEBI:37532)
12b-O-[Deca-2Z,4E-dienoyl]-13a-isobutyl-5-ene-7-oxo-4b-phorbol
(CHEBI:181979)
is a
phorbol ester
(CHEBI:37532)
16-hydroxyphorbol 13-decanoate 12-palmitate
(CHEBI:744)
is a
phorbol ester
(CHEBI:37532)
4α-phorbol 12,13-didecanoate
(CHEBI:139299)
is a
phorbol ester
(CHEBI:37532)
4-deoxyphorbol 12-acetate 13-(2Z,4E,6E)-deca-2,4,6-trienoate
(CHEBI:4941)
is a
phorbol ester
(CHEBI:37532)
[(1S,6R,10S,13S,14R,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-14-[(E)-2-methylbut-2-enoyl]oxy-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylbutanoate
(CHEBI:182074)
is a
phorbol ester
(CHEBI:37532)
[1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-13-(2-methylpropanoyloxy)-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] (E)-2-methylbut-2-enoate
(CHEBI:181555)
is a
phorbol ester
(CHEBI:37532)
[13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] (E)-2-methylbut-2-enoate
(CHEBI:181595)
is a
phorbol ester
(CHEBI:37532)
Candletoxin A
(CHEBI:3352)
is a
phorbol ester
(CHEBI:37532)
LSM-4341
(CHEBI:93813)
is a
phorbol ester
(CHEBI:37532)
pedilstatin
(CHEBI:743)
is a
phorbol ester
(CHEBI:37532)
phorbol 12,13-dibutanoate
(CHEBI:17598)
is a
phorbol ester
(CHEBI:37532)
phorbol 13-acetate
(CHEBI:45127)
is a
phorbol ester
(CHEBI:37532)
phorbol 13-acetate 12-myristate
(CHEBI:37537)
is a
phorbol ester
(CHEBI:37532)
phorbol 13-butanoate
(CHEBI:17727)
is a
phorbol ester
(CHEBI:37532)
phorbol 13-decanoate 12-tiglate
(CHEBI:28366)
is a
phorbol ester
(CHEBI:37532)
prostratin
(CHEBI:69818)
is a
phorbol ester
(CHEBI:37532)
rel-12-O-(4Z)-Deca-4-enoylphorbol-13-acetate
(CHEBI:70535)
is a
phorbol ester
(CHEBI:37532)
rel-12-O-(4Z,7Z)-Deca-4,7-dienoylphorbol-13-acetate
(CHEBI:70534)
is a
phorbol ester
(CHEBI:37532)
rel-12-O-Octanoylphorbol-13-acetate
(CHEBI:70536)
is a
phorbol ester
(CHEBI:37532)
rel-16-Angeloyloxy-13alpha-isobutanoyloxy-4beta,9alpha,20-trihydroxytiglia-1,5-diene-3,7-dione
(CHEBI:67863)
is a
phorbol ester
(CHEBI:37532)
rel-16-Angeloyloxy-13alpha-isobutanoyloxy-4beta,9alpha,7beta-trihydroxytiglia-1,5-dien-3-one
(CHEBI:67864)
is a
phorbol ester
(CHEBI:37532)
sapintoxin D
(CHEBI:72442)
is a
phorbol ester
(CHEBI:37532)
tigilanol tiglate
(CHEBI:194146)
is a
phorbol ester
(CHEBI:37532)
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17661218
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PubMed citation
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Europe PMC
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19944127
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PubMed citation
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Europe PMC
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27007372
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PubMed citation
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Europe PMC
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