dialurate (CHEBI:140629)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	dialurate

ChEBI ID	CHEBI:140629

Definition	A barbiturate anion resulting from deprotonation of the carbon bearing the hydroxy group of dialuric acid. Major microspecies at pH 7.3

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Anne Morgat

Supplier Information

Download	Molfile XML SDF

more structures >>

Formula

C4H3N2O4

Net Charge

-1

Average Mass

143.079

Monoisotopic Mass

143.00983

InChI

InChI=1S/C4H3N2O4/c7-1-2(8)5-4(10)6-3(1)9/h7H,(H2,5,6,8,9,10)/q-1

InChIKey

OYSYBUXEAFXXMH-UHFFFAOYSA-N

SMILES

N1C(NC([C-](C1=O)O)=O)=O

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via barbiturates )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via barbiturates )

ChEBI Ontology
Outgoing	dialurate (CHEBI:140629) is a barbiturate anion (CHEBI:22691) dialurate (CHEBI:140629) is conjugate base of dialuric acid (CHEBI:76452)

Incoming	dialuric acid (CHEBI:76452) is conjugate acid of dialurate (CHEBI:140629)

Synonym	Source
dialurate	UniProt

Citation	Type	Source
21344938	PubMed citation	SUBMITTER

Last Modified

31 January 2020