Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement to prevent and treat vitamin D deficiency due to poor absorption by the intestines or liver disease. It may also be used for low blood calcium due to hypoparathyroidism. It is taken by mouth or via injection into a muscle.
Excessive doses can result in vitamin D toxicity causing increased urine production, high blood pressure, kidney stones, kidney failure, muscle weakness, and constipation. If high doses are taken for a long period of time, tissue calcification may occur. Normal doses are safe in pregnancy. It works by increasing the amount of calcium absorbed by the intestines and reabsorbed by the kidneys. Food in which it is found include some mushrooms.
Ergocalciferol was first described in 1936. Ergocalciferol is available as a generic medication and over the counter. In 2022, it was the 38th most commonly prescribed medication in the United States, with more than 15 million prescriptions. Certain foods such as breakfast cereal and margarine have ergocalciferol added to them in some countries. It is on the World Health Organization's List of Essential Medicines.
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InChI=1S/2Na.H2O3Se.5H2O/c;;1-4(2)3;;;;;/h;;(H2,1,2,3);5*1H2/q2*+1;;;;;;/p-2 |
TUANAMBRHOLYTH-UHFFFAOYSA-L |
[Se](=O)([O-])[O-].[Na+].[Na+].O.O.O.O.O |
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nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
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View more via ChEBI Ontology
sodium selenite—water (1/5)
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disodium selenite hydrate
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ChEBI
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Na2SeO3·5H2O
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ChEBI
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Selenious acid disodium salt, pentahydrate
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ChemIDplus
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sodium selenite hydrate
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ChEBI
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Sodium selenite pentahydrate
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ChemIDplus
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14666014
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Reaxys Registry Number
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Reaxys
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26970-82-1
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CAS Registry Number
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ChemIDplus
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15259772
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PubMed citation
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Europe PMC
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15559373
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PubMed citation
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Europe PMC
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16126997
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PubMed citation
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Europe PMC
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17873396
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PubMed citation
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Europe PMC
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24479345
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PubMed citation
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Europe PMC
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24716537
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PubMed citation
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Europe PMC
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