Flutemazepam (CHEBI:188885)

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This entity has been annotated by a third party. If you would like more information added to this entry, please contact ChEBI via email or GitHub.

ChEBI Name	Flutemazepam

ChEBI ID	CHEBI:188885

Stars	This entity has been manually annotated by a third party.

Submitter	MetaboLights

Supplier Information

Download	Molfile XML SDF

Formula

C16H12ClFN2O2

Net Charge

Average Mass

318.730

Monoisotopic Mass

318.05713

InChI

InChI=1S/C16H12ClFN2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3

InChIKey

RMFYWNFETXNTIQ-UHFFFAOYSA-N

SMILES

ClC1=CC2=C(N(C(=O)C(O)N=C2C=3C(F)=CC=CC3)C)C=C1

Metabolite of Species	Details
Phyllostachys violascens (NCBI:txid1903417)	Found in stem (BTO:0001300). of strain Phyllostachys violascens cv. Viridisulcata See: MetaboLights Study

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	Flutemazepam (CHEBI:188885) is a benzodiazepine (CHEBI:22720)

IUPAC Name

7-chloro-5-(2-luorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one

Registry Number	Type	Source
52391-89-6	CAS Registry Number	ChemIDplus