CHEBI:76212 - triphenylmethane

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ChEBI Name triphenylmethane
ChEBI ID CHEBI:76212
Definition A triarylmethane in which the three aryl groups are phenyl. It forms the basic skeleton of several synthetic dyes.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB2724915, eMolecules:509860, ZINC000000097471
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Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Studies have shown that venlafaxine improves post-traumatic stress disorder (PTSD). It may also be used for chronic neuropathic pain. It is taken orally (swallowed by mouth). It is also available as the salt venlafaxine besylate (venlafaxine benzenesulfonate monohydrate) in an extended-release formulation (Venbysi XR). Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. There are concerns that use during the later part of pregnancy can harm the baby. How it works is not entirely clear, but it seems to be related to the potentiation of the activity of some neurotransmitters in the brain. Venlafaxine was approved for medical use in the United States in 1993. It is available as a generic medication. In 2022, it was the 44th most commonly prescribed medication in the United States, with more than 13 million prescriptions.
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Formula C19H16
Net Charge 0
Average Mass 244.33030
Monoisotopic Mass 244.12520
InChI InChI=1S/C19H16/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,19H
InChIKey AAAQKTZKLRYKHR-UHFFFAOYSA-N
SMILES c1ccc(cc1)C(c1ccccc1)c1ccccc1
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
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ChEBI Ontology
Outgoing triphenylmethane (CHEBI:76212) has role environmental contaminant (CHEBI:78298)
triphenylmethane (CHEBI:76212) has role xenobiotic (CHEBI:35703)
triphenylmethane (CHEBI:76212) is a triarylmethane (CHEBI:76214)
Incoming 4-{bis[4-(dimethylamino)phenyl]methyl}phenol (CHEBI:76210) has parent hydride triphenylmethane (CHEBI:76212)
IUPAC Name
1,1',1''-methanetriyltribenzene
Synonyms Sources
1,1',1''-methylidynetrisbenzene ChEBI
1,1,1-triphenylmethane ChEBI
Tritane ChemIDplus
Manual Xref Database
Triphenylmethane Wikipedia
View more database links
Registry Numbers Types Sources
1909753 Reaxys Registry Number Reaxys
519-73-3 CAS Registry Number ChemIDplus
Citations Types Sources
22573270 PubMed citation Europe PMC
23008002 PubMed citation Europe PMC
23053116 PubMed citation Europe PMC
23341885 PubMed citation Europe PMC
23865508 PubMed citation Europe PMC
24136473 PubMed citation Europe PMC
Last Modified
30 April 2014