CHEBI:65900 - fleephilone

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ChEBI Name fleephilone
ChEBI ID CHEBI:65900
Definition A organic heterotetracyclic compound isolated from the fermentation broth of Trichoderma harzianum and exhibits anti-HIV activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C24H27NO7
Net Charge 0
Average Mass 441.47370
Monoisotopic Mass 441.17875
InChI InChI=1S/C24H27NO7/c1-4-5-6-7-17-20-14-11-18(28)24(3,32-19(29)10-13(2)26)23(30)15(14)12-25-9-8-16(27)22(31-17)21(20)25/h4-7,11-13,16,21-22,26-27H,8-10H2,1-3H3/b5-4+,7-6+/t13?,16-,21+,22-,24?/m0/s1
InChIKey UOPRBHLVKJBASE-XVSBCJMYSA-N
SMILES [H][C@]12OC(\C=C\C=C\C)=C3C4=CC(=O)C(C)(OC(=O)CC(C)O)C(=O)C4=CN(CC[C@@H]1O)[C@@]23[H]
Metabolite of Species Details
Trichoderma harzianum (NCBI:txid5544) See: PubMed
Roles Classification
Biological Role(s): anti-HIV agent
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing fleephilone (CHEBI:65900) has functional parent 3-hydroxybutyric acid (CHEBI:20067)
fleephilone (CHEBI:65900) has role anti-HIV agent (CHEBI:64946)
fleephilone (CHEBI:65900) has role metabolite (CHEBI:25212)
fleephilone (CHEBI:65900) is a β-diketone (CHEBI:67265)
fleephilone (CHEBI:65900) is a carboxylic ester (CHEBI:33308)
fleephilone (CHEBI:65900) is a cyclic ether (CHEBI:37407)
fleephilone (CHEBI:65900) is a enone (CHEBI:51689)
fleephilone (CHEBI:65900) is a organic heterotetracyclic compound (CHEBI:38163)
fleephilone (CHEBI:65900) is a organonitrogen heterocyclic compound (CHEBI:38101)
fleephilone (CHEBI:65900) is a secondary alcohol (CHEBI:35681)
IUPAC Name
(2aR,3S,10cR)-3-hydroxy-8-methyl-7,9-dioxo-1-[(1E,3E)-penta-1,3-dien-1-yl]-2a,4,5,8,9,10c-hexahydro-3H,7H-2-oxa-5a-azaaceanthrylen-8-yl 3-hydroxybutanoate
Registry Number Type Source
183239-76-1 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
8968392 PubMed citation Europe PMC
Last Modified
25 January 2013