CHEBI:133008 - Epclusa

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ChEBI Name Epclusa
ChEBI ID CHEBI:133008
Definition A mixture composed of sofosbuvir and velpatasvir (trade name Epclusa) that is used for treatment of patients with chronic hepatitis C of all six major genotypes.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
hepatitis C protease inhibitor
An inhibitor of hepatitis C protease, an enzyme required for production of proteins needed for viral assembly.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Epclusa (CHEBI:133008) has part sofosbuvir (CHEBI:85083)
Epclusa (CHEBI:133008) has part velpatasvir (CHEBI:133009)
Epclusa (CHEBI:133008) has role antiviral drug (CHEBI:36044)
Epclusa (CHEBI:133008) has role hepatitis C protease inhibitor (CHEBI:64924)
Epclusa (CHEBI:133008) is a mixture (CHEBI:60004)
Synonyms Sources
Sofosbuvir and velpatasvir ChemIDplus
Sofosbuvir mixture with velpatasvir ChemIDplus
Sofosbuvir/velpatasvir ChemIDplus
Velpatasvir/Sofosbuvir ChemIDplus
Citations Waiting for Citations Types Sources
26551051 PubMed citation Europe PMC
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27135094 PubMed citation Europe PMC
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27444413 PubMed citation Europe PMC
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27508349 PubMed citation Europe PMC
Last Modified
15 August 2016
General Comment
2016-08-15 This mixture has a ChemIDplus substance accession number S900007160