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> Main
CHEBI:147356 - tilorone dihydrochloride
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ChEBI Name
tilorone dihydrochloride
ChEBI ID
CHEBI:147356
Definition
The dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS.
Stars
This entity has been manually annotated by the ChEBI Team.
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Molfile
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Molfile
Formula
C25H34N2O3.ClH.ClH
Net Charge
0
Average Mass
483.470
Monoisotopic Mass
482.21030
InChI
InChI=1S/C25H34N2O3.2ClH/c1-
5-
26(6-
2)
13-
15-
29-
19-
9-
11-
21-
22-
12-
10-
20(30-
16-
14-
27(7-
3)
8-
4)
18-
24(22)
25(28)
23(21)
17-
19;;/h9-
12,17-
18H,5-
8,13-
16H2,1-
4H3;2*1H
InChIKey
BSVYJQAWONIOOU-UHFFFAOYSA-N
SMILES
C1=2C=3C(C(C1=CC(=CC2)OCCN(CC)CC)=O)=CC(=CC3)OCCN(CC)CC.Cl.Cl
Roles Classification
Biological Role
(s):
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application
(s):
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
interferon inducer
An agent that promotes the production and release of interferons.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
tilorone dihydrochloride (
CHEBI:147356
)
has part
tilorone(2+) (
CHEBI:147355
)
tilorone dihydrochloride (
CHEBI:147356
)
has role
anti-inflammatory agent (
CHEBI:67079
)
tilorone dihydrochloride (
CHEBI:147356
)
has role
antineoplastic agent (
CHEBI:35610
)
tilorone dihydrochloride (
CHEBI:147356
)
has role
antiviral drug (
CHEBI:36044
)
tilorone dihydrochloride (
CHEBI:147356
)
has role
interferon inducer (
CHEBI:36710
)
tilorone dihydrochloride (
CHEBI:147356
)
has role
nicotinic acetylcholine receptor agonist (
CHEBI:47958
)
tilorone dihydrochloride (
CHEBI:147356
)
is a
hydrochloride (
CHEBI:36807
)
IUPAC Name
2,7-bis[2-(diethylamino)ethoxy]-9
H
-fluoren-9-one dihydrochloride
Synonyms
Sources
tilorone HCl
ChemIDplus
tilorone hydrochloride
ChemIDplus
Brand Names
Sources
Amixin
ChEBI
Lavomax
ChEBI
Manual Xrefs
Databases
D06149
KEGG DRUG
DBSALT003375
DrugBank
View more database links
Registry Number
Type
Source
27591-69-1
CAS Registry Number
ChemIDplus
Citations
Types
Sources
10769698
PubMed citation
Europe PMC
124872
PubMed citation
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16758904
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7291725
PubMed citation
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7446671
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809901
PubMed citation
Europe PMC
879763
PubMed citation
Europe PMC
Last Modified
10 May 2024