CHEBI:48668 - γ-secretase modulator

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ChEBI Name γ-secretase modulator
ChEBI ID CHEBI:48668
ChEBI ASCII Name gamma-secretase modulator
Definition A modulator of γ-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing γ-secretase modulator (CHEBI:48668) is a effector (CHEBI:35224)
Incoming 2-[5-(4-fluorophenoxy)-4'-(trifluoromethyl)biphenyl-3-yl]pentanoic acid (CHEBI:48658) has role γ-secretase modulator (CHEBI:48668)
2-[5-phenoxy-4'-(trifluoromethyl)biphenyl-3-yl]pentanoic acid (CHEBI:48659) has role γ-secretase modulator (CHEBI:48668)
auraptene (CHEBI:134355) has role γ-secretase modulator (CHEBI:48668)
nirogacestat (CHEBI:229217) has role γ-secretase modulator (CHEBI:48668)
nirogacestat dihydrobromide (CHEBI:229218) has role γ-secretase modulator (CHEBI:48668)
Synonyms Sources
gamma secretase modulator ChEBI
gamma secretase modulators ChEBI
Γ-secretase modulator ChEBI
gamma-secretase modulator ChEBI
Γ-secretase modulators ChEBI
gamma-secretase modulators ChEBI
γ-secretase modulators ChEBI
Manual Xref Database
Gamma_secretase Wikipedia
View more database links
Last Modified
16 January 2024
General Comment
2008-04-21 MeSH D08.811.277.656.300.032 : gamma-secretase