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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:497734 -
L
-thialysine
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ChEBI Name
L
-thialysine
ChEBI ID
CHEBI:497734
ChEBI ASCII Name
L-thialysine
Definition
A cysteine derivative that is the
S
-(2-aminoethyl) analogue of
L
-cysteine; reported to have cytotoxic effects.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:45515
Supplier Information
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Wikipedia
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Read full article at Wikipedia
Formula
C5H12N2O2S
Net Charge
0
Average Mass
164.22600
Monoisotopic Mass
164.06195
InChI
InChI=1S/C5H12N2O2S/c6-1-2-10-3-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
InChIKey
GHSJKUNUIHUPDF-BYPYZUCNSA-N
SMILES
NCCSC[C@H](N)C(O)=O
Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Br
o
nsted base).
(via
oxoacid
)
Biological Role
(s):
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
L
-thialysine (
CHEBI:497734
)
has role
EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor (
CHEBI:75190
)
L
-thialysine (
CHEBI:497734
)
has role
metabolite (
CHEBI:25212
)
L
-thialysine (
CHEBI:497734
)
has role
protein synthesis inhibitor (
CHEBI:48001
)
L
-thialysine (
CHEBI:497734
)
is a
L
-cysteine thioether (
CHEBI:27532
)
L
-thialysine (
CHEBI:497734
)
is a
non-proteinogenic
L
-α-amino acid (
CHEBI:83822
)
L
-thialysine (
CHEBI:497734
)
is conjugate base of
L
-thialysinium (
CHEBI:156132
)
Incoming
N
-acetyl-
L
-thialysine (
CHEBI:156139
)
has functional parent
L
-thialysine (
CHEBI:497734
)
L
-thialysinium (
CHEBI:156132
)
is conjugate acid of
L
-thialysine (
CHEBI:497734
)
IUPAC Name
S
-(2-aminoethyl)-
L
-cysteine
Synonyms
Sources
(2R)-2-amino-3-(2-aminoethylsulfanyl)propanoic acid
PDB
(R)-2-amino-3-(2-aminoethylthio)propanoic acid
ChEMBL
2-Aminoethylcysteine
HMDB
4-Thia-L-lysine
HMDB
4-Thialysine
HMDB
Aminoethylcysteine
ChemIDplus
gamma-Thia-lys
ChemIDplus
gamma-Thialysine
ChemIDplus
S-2-Aminoethyl cysteine
ChemIDplus
S-beta-Aminoethyl cysteine
ChemIDplus
Thiosine
ChemIDplus
Manual Xrefs
Databases
HMDB0033518
HMDB
S-Aminoethyl-L-cysteine
Wikipedia
View more database links
Registry Numbers
Types
Sources
1006349
Gmelin Registry Number
Gmelin
1705488
Reaxys Registry Number
Reaxys
2936-69-8
CAS Registry Number
ChemIDplus
Citations
Types
Sources
11370852
PubMed citation
Europe PMC
17165731
PubMed citation
Europe PMC
17524640
PubMed citation
ChEMBL
19634897
PubMed citation
Europe PMC
19685884
PubMed citation
Europe PMC
7654708
PubMed citation
Europe PMC
Last Modified
14 July 2020