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AM6545 |
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CHEBI:231613 |
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A member of the class of pyrazoles that is 1H-pyrazole substituted by 2,4-dichlorophenyl, N-(1,1-dioxidothiomorpholin-4-yl)aminoacyl, methyl, and 4-(4-cyanobut-1-yn-1-yl)phenyl groups at positions 1, 3, 4 and 5, respectively. It is a cannabinoid receptor 1 antagonist and a potential appetite suppressant. |
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This entity has been manually annotated by the ChEBI Team.
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Alexandra Millett
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ChemicalBook:CB4129374, eMolecules:2728948, Selleckchem:rimonabant-sr141716, ZINC000001540228 |
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Molfile
XML
SDF
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InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) |
XBHQLFVDGLPBCK-UHFFFAOYSA-N |
CC1=C(N(N=C1C(=O)NN1CCS(=O)(=O)CC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(C=C1)C#CCCC#N |
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CB1 receptor antagonist
An antagonist that binds to and deactivates type 1 cannabinoid receptors.
anti-obesity agent
Any substance which is used to reduce or control weight.
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appetite depressant
Any agent that is used to decrease appetite.
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View more via ChEBI Ontology
5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxidothiomorpholin-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
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5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxo-1λ6,4-thiazinan-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
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SUBMITTER
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5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxo-1λ6-thiomorpholin-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
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ChEBI
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AM 6545
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SUBMITTER
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AM-6545
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SUBMITTER
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1245626-05-4
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CAS Registry Number
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SUBMITTER
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20664173
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